Search

Displaying results 4541 - 4550 of 10000 in total
  1. Drug

    Sobuzoxane

    go.drugbank.com/drugs/DB21119
    Experimental

    Sobuzoxane is a small molecule drug. The usage of the INN stem '-oxan(e)' in the name indicates that Sobuzoxane is a benzodioxane derivative.

    Categories: Topoisomerase II Inhibitors
  2. Drug

    Loteprednol

    go.drugbank.com/drugs/DB00873
    ApprovedInvestigationalWithdrawn

    Loteprednol is a corticosteroid. A more commonly used formulation of loteprednol is its ester, [loteprednol etabonate].

  3. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904] … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors.

  4. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

  5. Drug

    Larazotide

    go.drugbank.com/drugs/DB05645
    Investigational

    An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.

  6. Drug

    SC-236

    go.drugbank.com/drugs/DB14059
    Experimental

    SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) [L2964] that has been studied in cancer therapy [A33375], lower back pain [A33376], and inflammation [A33373], [A33374

  7. Drug

    Nitrazepam

    go.drugbank.com/drugs/DB01595
    Approved

    A benzodiazepine derivative used as an anticonvulsant and hypnotic.

    Synonyms: N-desmethylnimetazepamProducts: EATAN N
  8. Drug

    AVI-4065

    go.drugbank.com/drugs/DB05620
    Investigational

    AVI-4065, a phosphorodiamidate Morpholino oligomer (PMO), is an investigational antisense HCV drug. It was developed by Sarepta Therapeutics, Inc. … After phase II trials it was cancelled due to lack of potency. [L2917]

  9. Drug

    Epicriptine

    go.drugbank.com/drugs/DB11275
    Approved

    Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from the alpha form on the position of one methyl group. … Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine.

  10. Drug

    RP01

    go.drugbank.com/drugs/DB05751
    Experimental

    It is designed to induce the immune system to produce antibodies that block Immunoglobulin E (IgE), the key mediator of an allergic response. … RP01 is a novel anti-IgE immunotherapy for allergic individuals.