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Galsulfase

Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular

PA-1050040

PA1050040, a second generation HIV-1 maturation inhibitor, is a chemical analog of Bevirimat (BVM). It inhibits virus replication by the same mechanism of action as BVM.

RLYB212

RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.

LG-100268

LG-100268 is a retinoid X receptor (RXR) selective compound.

1alpha,24S-Dihydroxyvitamin D2

LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. … Studies have shown LR-103 has the same potency as calcitriol, but much lower toxicity.

Otilimab

Investigated for the treatment of osteoarthritis and rheumatoid arthritis (RA).

LY-2183240

LY-2183240 is an inhibitor of endocannabinoid reuptake/breakdown.[A253037]

Mechlorethamine

A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. … The FDA granted marketing approval for the orphan drug Valchlor (mechlorethamine) gel on August 23, 2013 for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL

Penbutolol

Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. … Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker.

Darapladib