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Elranatamab
go.drugbank.com/drugs/DB15395ApprovedInvestigationalElranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. … It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one
Categories: Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engagerSynonyms: IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN)), HUMAN-MUS MUSCULUS MONOCLONAL DISULFIDE WITH IMMUNOGLOBULIN, B-CELL MATURATION ANTIGEN (BCMA) CLUSTER OF DIFFERENTIATION 3 (CD3) BISPECIFIC MONOCLONAL ANTIBODY (MAB) ANTI-BCMA/ANTI-CD3 BISPECIFIC MABNicotinamide
go.drugbank.com/drugs/DB02701ApprovedInvestigationalAn important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. … Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Mixtures: MU LAB TURN AROUND 2W Refresh Ex, Tonicol Et A-D-C Ampoules/comprimesCategories: Heterocyclic Compounds, 1-Ring, Vitamin B ComplexFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalFondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. … Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold.
Categories: Factor Xa Inhibitors, Indirect factor Xa inhibitorsProducts: ARIXTRA 5MG/0.4 ML S.S. ENJ. COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 2 ADET, ARIXTRA ® 7.5 MG /0.6 MLAtazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationalLike other protease inhibitors, it is used only in combination with other HIV medications. The U.S. Food and Drug Administration (FDA) approved atazanavir on June 20, 2003. … Atazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol
Mixtures: ANCEF ® R, ANCEF ® RCategories: Heterocyclic Compounds, 1-Ring, Antivirals used in combination for the treatment of HIV infectionsEssential Thrombocythemia (ET)
go.drugbank.com/conditions/DBCOND0048758Synonyms: ET (Essential Thrombocythemia), Essential Thrombocythemia (ET)Canrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnCanrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Products: POTASSIO CANRENOATO EG, Aldactone 200 mg/ 10 ml InjektionslösungPoractant alfa
go.drugbank.com/drugs/DB09113ApprovedInvestigationalPoractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. It contains no preservatives. … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada.
Products: CUROSURF 240 MG/3 ML INTRATRAKEAL SUSPANSIYON IÇEREN FLAKON, 1 ADET, CUROSURF 120 MG/1,5 ML INTRATRAKEAL SUSPANSIYON IÇEREN FLAKON, 1 ADETDenosumab
go.drugbank.com/drugs/DB06643ApprovedInvestigational; Both biosimilars also received marketing authorization in the EU in May 2024. … Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of
Products: XGEVA 120 MG SC. ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET, PROLIA 60 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADETGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … [A233565] Glycopyrronium was originally granted FDA approval on 11 August 1961.[L33090]
Mixtures: TRYDONİS 87 MCG/5 MCG/9 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 120 DOZ, TRİMBOW 87/5/9 MCG AEROSOL İNHALASYON ÇÖZELTİSİ, 120 DOZCategories: MATE 1 Substrates, Heterocyclic Compounds, 1-RingTrihexyphenidyl
go.drugbank.com/drugs/DB00376ApprovedInvestigational[A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant adverse effects. … [L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity.
Categories: Heterocyclic Compounds, 1-RingInternational brands: Ea Ten