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Displaying results 4581 - 4590 of 10000 in total
  1. Drug

    Practolol

    go.drugbank.com/drugs/DB01297
    Approved

    A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.

  2. Drug

    Phenoxybenzamine

    go.drugbank.com/drugs/DB00925
    ApprovedInvestigational

    An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

  3. Drug

    Asimadoline

    go.drugbank.com/drugs/DB05104
    Investigational

    Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. … Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis.

  4. Drug

    105AD7

    go.drugbank.com/drugs/DB05113
    Investigational

    metastatic colorectal cancer patients. 105AD7 may be a suitable vaccine for treatment of this disease. … 105AD7 is a human monoclonal antibody that mimics the complement regulatory protein, CD55, overexpressed by many solid tumours including osteosarcoma. 105AD7 induced antitumour inflammatory responses in

  5. Drug

    Enzalutamide d3

    go.drugbank.com/drugs/DB19123
    Investigational

    Enzalutamide d3 is under investigation in clinical trial NCT03850795 (HC-1119 Versus Enzalutamide in Metastatic Castration-resistant Prostate Cancer (Mcrpc)).

    Synonyms: Enzalutamide d3, 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl)-2-fluoro-n-(methyl-d3)benzamide
  6. Drug

    1alpha-Hydroxyvitamin D5

    go.drugbank.com/drugs/DB13097
    Investigational

    1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.

    Categories: Vitamin D and AnaloguesSynonyms: 1-Hydroxyvitamin D5
  7. Drug

    Mipicoledine

    go.drugbank.com/drugs/DB15075
    Investigational

    Mipicoledine is under investigation in clinical trial NCT01048008 (Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer).

    Synonyms: DM-CHOC-PEN
  8. Drug

    Lavamilast

    go.drugbank.com/drugs/DB19767
    Experimental

    Lavamilast has a monoisotopic molecular weight of 520.16 Da. … Lavamilast is a small molecule drug. The usage of the INN stem '-milast' in the name indicates that Lavamilast is a Phosphodiesterase-4 (PDE4) inhibitor.

  9. Drug

    Itacnosertib

    go.drugbank.com/drugs/DB21463
    Experimental

    Itacnosertib has a monoisotopic molecular weight of 468.24 Da. … Itacnosertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Itacnosertib is a serine/threonine kinase inhibitor.

  10. Drug

    Cotosudil

    go.drugbank.com/drugs/DB21482
    Experimental

    Cotosudil has a monoisotopic molecular weight of 319.14 Da. … Cotosudil is a small molecule drug. The usage of the INN stem '-sudil' in the name indicates that Cotosudil is a Rho protein kinase inhibitor.