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Cefiderocol
go.drugbank.com/drugs/DB14879ApprovedInvestigational[L10893] It is indicated for use in complicated urinary tract infections in patients with limited or no alternative treatments available. … Cefiderocol was granted designation as a Qualified Infectious Disease Product and granted priority review status by the FDA on November 14, 2019.
Alginic acid
go.drugbank.com/drugs/DB13518ApprovedInvestigationalWithdrawnIt is also available in oral dietary supplements and is found in antacids such as Gaviscon to inhibit gastroesophageal reflux by creating a physical barrier in presence of gastric acid [F46]. … Available in different types of salt, alginic acid has been used in a variety of uses in food, cosmetics and pharmaceu-tical products for over 100 years [A32961].
Benzonatate
go.drugbank.com/drugs/DB00868Approved[A5790] Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. … Benzonatate was approved by the FDA in 1958 under the market name Tessalon Perles.
Lemborexant
go.drugbank.com/drugs/DB11951ApprovedInvestigational[L10863] Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits, but rather an inability to … Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance.
Cyanocobalamin
go.drugbank.com/drugs/DB00115ApprovedInvestigationalNutraceuticalThis drug was initially approved by the FDA in 1942 [FDA label]. … This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular energy production.
Dabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigational[A177463] Dabigatran etexilate was approved by the FDA in 2010.[L6022]
Technetium Tc-99m mebrofenin
go.drugbank.com/drugs/DB09137ApprovedWithdrawnCurrently available within a sterile kit, Tc-99m Mebrofenin is indicated for imaging of the liver and gallbladder. … This is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray.
Irinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer. … [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic adenocarcinoma.
Baloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[L4779] It was also approved by the European Commission on January 7, 2021.[L45241] … [A251760] Baloxavir marboxil was first globally approved in Japan in February 2018,[A39895] followed by the US approval in October, 2018.
Paclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedIt is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane.