Search
Chlorpheniramine
go.drugbank.com/drugs/DB01114ApprovedInvestigationalA histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications.
Mixtures: KATARİN 250 MG/100 MG/2 MG KAPSÜL, 15 ADET, KATARİN 250 MG/100 MG/2 MG KAPSÜL, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsDeferoxamine
go.drugbank.com/drugs/DB00746ApprovedInvestigationalIt forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Deferrioxamine BRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalHowever there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … FDA approved on July 1, 2011.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: RIVAROXABAN EG, RIVAROXABAN EG STADABrivaracetam
go.drugbank.com/drugs/DB05541ApprovedInvestigationalBrivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184]. … It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 [L760].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: BRIVIACT ® 50 MG COMPRIMIDOS RECUBIERTOS., BRIVIACT ® 25 MG COMPRIMIDOS RECUBIERTOS.Dorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and
Mixtures: Cosopt 20 mg/ml + 5 mg/ml Augentropfen, Dorzastad 20 mg/ml + 5 mg/ml AugentropfenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesItraconazole
go.drugbank.com/drugs/DB01167ApprovedInvestigational[A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. … First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections.
Mixtures: ITRACONAZOL 33.3 MG + SECNIDAZOL 166.66 MG CÁPSULA, Ciclopirox 3% / Itraconazole 5% / Urea 20%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsCromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalA chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.
Mixtures: OSMOCROM-N ®Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalBromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion.
Mixtures: PENBRITIN EX, PENAMOX MSynonyms: N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamineCrizotinib
go.drugbank.com/drugs/DB08865ApprovedInvestigational[A250785] Crizotinib was approved by the FDA in 2011, and its use is accompanied by FDA-approved tests used to detect ALK and ROS1 rearrangements.[L42460] … [L42460] By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, crizotinib offers robust effectiveness in treating NSCLC in patients with this type of rearrangement
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (R)-crizotinibIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: D-Isosorbide dinitrate