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Aminophylline
go.drugbank.com/drugs/DB01223ApprovedInvestigationalSimilar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: AMINOCARDOL 10 ML 240 MG 100 AMPUL, TECAR 240 MG/10 ML IV INFUZYON COZELTISI ICEREN AMPUL, 100 ADETDexmedetomidine
go.drugbank.com/drugs/DB00633ApprovedInvestigationalVet approvedAn agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: SEMOTİDİN 200 MCG/50 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET, PRECEDEX® 200MCG/50 ML (4MCG/ML)Magrolimab
go.drugbank.com/drugs/DB16225InvestigationalMagrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Synonyms: Immunoglobulin g4-kappa, anti-(homo sapiens cd47 (integrin associated protein, iap, mer6, oa3)), monoclonal antibodygamma4 heavy chain (1-444) (vh (homo sapiens ighv1-3*01 (87.8%)-(ighd)-ighj4*01 (100%Acarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigational[L31668] This class of antidiabetic therapy is not widely used due to their relatively modest impact on A1c, their requirement for thrice-daily dosing, and the potential for significant gastrointestinal … [L31633,A37868] By inhibiting the activity of these enzymes, acarbose limits the absorption of dietary carbohydrates and the subsequent postprandial increase in blood glucose and insulin levels.
Products: ACNOR 100 MG TABLET, 60 ADET, GLUCOBAY 100 TABLET 100 mgHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[A189753] Hydroxyzine is also used for generalized anxiety disorder, tension caused by psychoneurosis, and other conditions with manifestations of anxiety.[L9677]
Mixtures: ATARAX FILM TABLET, 30 ADET, ATARAX FILM TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approvedA benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Synonyms: O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate, 5-(propylthio)-2-carbomethoxyaminobenzimidazoleMixtures: LO-BRUQUINPegvorhyaluronidase alfa
go.drugbank.com/drugs/DB14912InvestigationalPegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection
Synonyms: ALFA, SUBSTITUTED ON N6 OF AN AVERAGE OF 4 TO, HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR-(36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORMAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigational[A178090] Atomoxetine has been shown to specifically increase NA and DA within the prefrontal cortex, but not in the nucleus accumbens (NA) or striatum. … of other drugs of abuse such as amphetamines, making ADHD sufferers more susceptible to their addictive effects.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: STRATTERA 10 MG, audalis 10 mg FilmtablettenSucralfate
go.drugbank.com/drugs/DB00364ApprovedInvestigational, peptic ulcer disease, stress ulcer, in addition to dyspepsia [A177655]. … Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms.
Synonyms: Hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-Dfructofuranosyl-α-D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminumMixtures: CARDIBID®100/200 MG TABLETA RECUBIERTASuccinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigationalIts rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and lasting between four to six minutes, make succinylcholine particularly useful in the setting of short … Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.
Products: QUELICIN 1000 MG/10 ML, ETHICHOLINE INJECTION 100 mg/2 ml