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Displaying results 451 - 460 of 10000 in total
  1. Drug

    Ganirelix

    go.drugbank.com/drugs/DB06785
    ApprovedInvestigational

    Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999.

    Products: NOVOLEX 0.25 MG/0.5 ML SOLUCIÓN INYECTABLE EN JERINGA PRECARGADA, Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze
  2. Drug

    Sorafenib

    go.drugbank.com/drugs/DB00398
    ApprovedInvestigational

    Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. … It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis.

    Synonyms: N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea, 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamideCategories: UGT1A9 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  3. Drug

    Cephalexin

    go.drugbank.com/drugs/DB00567
    ApprovedInvestigationalVet approved

    [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971. … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide.

    Synonyms: (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acidInternational brands: L-Keflex
  4. Drug

    Vancomycin

    go.drugbank.com/drugs/DB00512
    ApprovedInvestigational

    It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. … Such an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196].

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: VANCOMICINA BONISCONTRO E GAZZONE, Vancomycin Dr. Eberth 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung oder zur Herstellung einer Lösung zum Einnehmen
  5. Drug

    Neomycin

    go.drugbank.com/drugs/DB00994
    ApprovedInvestigationalVet approved

    [L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. … [L11985] Neomycin sulfate is the most common form for pharmaceutical preparations; because the compound is a complex, the amount of neomycin in products is measured in units.

    Mixtures: Pomada De La Campana Triple Antibiotic Pain Relief, Tribioticlc Lc LcCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  6. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Categories: Arteriolar Smooth Muscle, Agents Acting OnProducts: LE PHOQUA Hair Regrowth Serum BIOTIN 5% MINOXIDIL, TRIATOP®ESPUMA TÓPICA EN AEROSOL
  7. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis. … [A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood.

    Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: D-FUMARIC 240 CAPSULAS DE LIBERACIÓN RETARDADA 240 MG, D-FUMARIC 120 CAPSULAS DE LIBERACION RETARDADA 120 MG
  8. Drug

    Silver proteinate

    go.drugbank.com/drugs/DB16362
    Investigational

    Products: ARGENTO PROTEINATO MARCO VITI
  9. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    [A39076] On the available products, ibuprofen is administered as a racemic mixture. … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.

    Mixtures: ADVIL® CONTRA LOS SÍNTOMAS DE LA GRIPA MULTISINTOMAS, ADVIL® CONTRA LOS SÍNTOMAS DE LA GRIPA MULTISINTOMASProducts: FEMEN CAPSULAS DE GELATINA BLANDA, IBUPROFEN 400MG FTA STA LE
  10. Drug

    Potassium permanganate

    go.drugbank.com/drugs/DB13831
    Investigational

    Categories: Compounds used in a research, industrial, or household settingProducts: POTASSIO PERMANGANATO MARCO VITI