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Displaying results 4601 - 4610 of 10000 in total

Drug
Tyrosinase
go.drugbank.com/drugs/DB16626
Investigational
as melanogenesis). … [A231829, A231839] It is recognized as being the main enzyme responsible for enzymatic browning and melanogenesis in mammals, thus causing undesired browning of fruits and vegetables and diseases resulting
Drug
Tilarginine
go.drugbank.com/drugs/DB11815
ApprovedInvestigationalWithdrawn
Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.
Synonyms: N-Methylarginine, N(G)-Methylarginine
Drug
Piroximone
go.drugbank.com/drugs/DB19750
Experimental
Piroximone has a monoisotopic molecular weight of 217.09 Da.
Categories: Compounds used in a research, industrial, or household setting
Drug
Mecrylate
go.drugbank.com/drugs/DB21343
Experimental
Mecrylate has a monoisotopic molecular weight of 111.03 Da.
Categories: Compounds used in a research, industrial, or household setting
Drug
Dimetacrine
go.drugbank.com/drugs/DB08996
ApprovedWithdrawn
Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. … Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in Europe for the treatment of depression. Dimetacrine is no longer used in Japan.
Synonyms: 3-(9,9-dimethylacridin-10-yl)-N,N-dimethyl-propan-1-amine
Drug
ANA971
go.drugbank.com/drugs/DB05127
Experimental
ANA971 resulted in higher levels of isatoribine in the blood than were present after oral administration of isatoribine itself. … ANA971, an orally administered prodrug of isatoribine. Isatoribine is a nucleoside analog in development for the treatment of chronic hepatitis C virus (HCV) infection.
Drug
Z-Val-Ala-Asp fluoromethyl ketone
go.drugbank.com/drugs/DB07744
Experimental
Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. … It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamide
Drug
Ametantrone
go.drugbank.com/drugs/DB21078
Experimental
Ametantrone has a monoisotopic molecular weight of 412.21 Da.
Categories: Compounds used in a research, industrial, or household setting
Drug
Cyclandelate
go.drugbank.com/drugs/DB04838
ApprovedWithdrawn
Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries.
Drug
Recombinant Bacterial ACE2 Receptors-like Enzyme
go.drugbank.com/drugs/DB15741
Investigational
B38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2 … B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.