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5-methyltetrahydrofolic acid
go.drugbank.com/drugs/DB04789InvestigationalNutraceutical5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. … It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases
Synonyms: 5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid, N-MethyltetrahydrofolateInternational brands: Prefolic A6-Hydroxy-5-undecyl-4,7-benzothiazoledione
go.drugbank.com/drugs/DB04799ExperimentalCategories: Heterocyclic Compounds, 1-RingSynonyms: 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole, 6-Hydroxy-5-undecyl-4,7-benzothiazoledioneClioquinol
go.drugbank.com/drugs/DB04815ApprovedVet approvedWithdrawnClioquinol was withdrawn in 1983 due to neurotoxicity.
Mixtures: BETNOVATE-C % 0,1 + % 3 KREM, 5 GR, BETNOVATE-C % 0,1 + % 3 MERHEM, 5 GRCategories: Heterocyclic Compounds, 2-RingDantron
go.drugbank.com/drugs/DB04816ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Mixtures: Regulex D CapInternational brands: Scatron DZomepirac
go.drugbank.com/drugs/DB04828ApprovedWithdrawnThe manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983. … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acidZimelidine
go.drugbank.com/drugs/DB04832ApprovedWithdrawnZimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving
Categories: P-glycoprotein inhibitors, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: (Z)-3-(4'-Bromophenyl)-3-(3''-pyridyl)dimethylallylamine, (Z)-zimelidineAmineptine
go.drugbank.com/drugs/DB04836ApprovedIllicitWithdrawnThe Food and Drug Administration suspended the marketing authorisation for Survector in 1999 and France withdrew it from the market, however several developing countries continued to produce it up until 2005.
Cyclandelate
go.drugbank.com/drugs/DB04838ApprovedWithdrawnCyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries. … A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates