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Displaying results 4651 - 4660 of 10000 in total
  1. Drug

    Pegmusirudin

    go.drugbank.com/drugs/DB19220
    Investigational

    Pegmusirudin is under investigation in clinical trial NCT00074620 (A Clinical Study to Assess the Safety of Peg-hirudin (SPP200) Compared to Heparin in Patients Who Are on Haemodialysis).

  2. Drug

    AG-858

    go.drugbank.com/drugs/DB05502
    Investigational

    Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models.

  3. Drug

    Teglarinad chloride

    go.drugbank.com/drugs/DB05217
    Investigational

    In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. … Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis.

  4. Target

    Probable ATP-dependent RNA helicase DDX5

    go.drugbank.com/bio_entities/BE0009162
    TargetHumans

    Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream ...

    Synonyms: DEAD box protein 5
  5. Drug

    Favipiravir

    go.drugbank.com/drugs/DB12466
    ApprovedInvestigational

    Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza. … [A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, and may be an alternative option for

  6. Drug

    Evobrutinib

    go.drugbank.com/drugs/DB15170
    Investigational

    Evobrutinib is under investigation in clinical trial NCT03934502 (Effect of Meal Composition and Timing on Evobrutinib Bioavailability).

  7. Drug

    C-peptide

    go.drugbank.com/drugs/DB16187
    Investigational

    C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).

  8. Drug

    Zifibancimig

    go.drugbank.com/drugs/DB19332
    Investigational

    Zifibancimig is under investigation in clinical trial NCT04567303, focusing on participants with neovascular age-related macular degeneration.

  9. Drug

    Metacycline

    go.drugbank.com/drugs/DB00931
    Approved

    A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.

  10. Indication

    Premature Births

    go.drugbank.com/conditions/DBCOND0043809
    Drugs: Atosiban · Hydroxyprogesterone caproate · Ritodrine
    Synonyms: Baby born premature