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Displaying results 4661 - 4670 of 10000 in total
  1. Drug

    Tesevatinib

    go.drugbank.com/drugs/DB11973
    Investigational

    In addition, tesevatinib inhibits EphB4, an RTK that is highly expressed in many human tumors and plays a role in promoting angiogenesis. … Tesevatinib is a potent inhibitor of multiple RTKs implicated in driving tumor cell proliferation and tumor vascularization (blood vessel formation).

  2. Drug

    KAI-1455

    go.drugbank.com/drugs/DB06064
    Experimental

    In preclinical studies, KAI-1455 showed a dramatic reduction in infarct size when delivered prior to the ischemic insult. … Several studies have demonstrated that epsilon PKC plays a key role in cytoprotection during periods of ischemia.

  3. Drug

    AEOL-10150

    go.drugbank.com/drugs/DB05874
    Experimental

    AEOL 10150 is developed by Aeolus as a therapeutic agents based on its proprietary small molecule catalytic antioxidants.

  4. Drug

    Prajmaline

    go.drugbank.com/drugs/DB13555
    Experimental

    Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class Ia
  5. Drug

    Strychnine

    go.drugbank.com/drugs/DB15954
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Tocotrienol

    go.drugbank.com/drugs/DB12647
    Investigational

    Tocotrienol has been investigated for the treatment of Cholesterol Lowering.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    8-anilinonaphthalene-1-sulfonic acid

    go.drugbank.com/drugs/DB04474
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Plinabulin

    go.drugbank.com/drugs/DB05992
    Investigational

  9. Drug

    SL017

    go.drugbank.com/drugs/DB05156
    Experimental

    SL017 formulated as a topical gel, has been combined with a widely available light source for permanent removal of unwanted hair and for treatment of actinic keratosis

  10. Drug

    Fendiline

    go.drugbank.com/drugs/DB08980
    ApprovedWithdrawn

    Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. … Fendiline is non-selective.