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Displaying results 4661 - 4670 of 10000 in total
  1. Drug

    Pentoxyverine

    go.drugbank.com/drugs/DB11186
    ApprovedWithdrawn

    Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate. … Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and local anesthetic properties.

    Mixtures: Pancold A, GAYABEN 150 ML SURUPProducts: PENTOXYVERIN AL 1.35 MG/ML, PENTOXYVERIN AL 19MG/ML
  2. Drug

    Menadione

    go.drugbank.com/drugs/DB00170
    ApprovedNutraceutical

    A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

    Mixtures: LIBAVIT-K 20 MG AMPUL, 5 ADETCategories: Vitamin K, Cytochrome P-450 CYP1A2 Inducers
  3. Drug

    Metamizole

    go.drugbank.com/drugs/DB04817
    ApprovedInvestigationalWithdrawn

    Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. … Approvals of the NDA's for metamizole drug products were withdrawn on June 27, 1977 (see the Federal Register of June 17, 1977, 42 FR 30893).

    Mixtures: N-BUTIL BROMURO DE HIOSCINA20MG + DIPIRONA 2500 MG/5 ML, DIPIRONA SODICA 2.5G/5ML + N- BUTILBROMURO DE HIOSCINA 20 MG/5ML SOLUCION INYECTABLECategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A Inducers
  4. Drug

    Clodronic acid

    go.drugbank.com/drugs/DB00720
    ApprovedInvestigationalVet approved

    Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid]. … [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.

    Products: ACIDO CLODRONICO EG, BONEFOS 800 MG TABLET, 60 ADET
  5. Drug

    Desvenlafaxine

    go.drugbank.com/drugs/DB06700
    ApprovedInvestigational

    [L6016,A261271] MDD is a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and 12.8% in Europe. … [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: O-desmethylvenlafaxine
  6. Drug

    Bromazepam

    go.drugbank.com/drugs/DB01558
    ApprovedIllicit

    It is a intermediate-acting benzodiazepine. … One of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: BROMAZEPAM N&P, BROMAZEPAM EG
  7. Indication

    Invasive Meningococcal Disease caused by Neisseria meningitidis serogroup A

    go.drugbank.com/conditions/DBCOND0165273
    Drugs: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine · Meningococcal polysaccharide vaccine group A · Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen · Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen
    Synonyms: Invasive Infection caused by Neisseria meningitidis serogroup A, Invasive Meningococcal Disease caused by Neisseria meningitidis serogroup A
  8. Drug

    Gadodiamide

    go.drugbank.com/drugs/DB00225
    ApprovedInvestigational

    Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels. … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents.

    Categories: Compounds used in a research, industrial, or household settingProducts: OMNISCAN® INYECTABLE, OMNISCAN INJECTION 0.5MMOL/ML-10ML IN GLASS VIAL
  9. Drug

    Witch hazel

    go.drugbank.com/drugs/DB11111
    ApprovedInvestigationalNutraceutical

    Mixtures: HAMAZINC KREM ,90 G, HAMAZINC KREM ,30 GProducts: Placenta EX Deep Line, A Breath of Fresh Air
  10. Drug

    Gabapentin

    go.drugbank.com/drugs/DB00996
    ApprovedInvestigational

    Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the United States in 1993. … [A14097,A186179] Gabapentin has some stark advantages as compared with other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and lack of appreciable metabolism

    Mixtures: GAVINDO N, Innoprax-5Synonyms: 1-(Aminomethyl)cyclohexaneacetic acid