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TRGFT-201
go.drugbank.com/drugs/DB23064ApprovedInvestigational[L64070] It is a precision-engineered graft composed of three cell populations isolated from an HLA-matched donor's mobilized peripheral blood — purified hematopoietic stem and progenitor cells (HSPCs) … [L64070,L64071] This composition is designed to improve survival free of chronic GVHD compared with a conventional transplant.
Albumin human
go.drugbank.com/drugs/DB00062ApprovedInvestigationalEach domain comprises two separate sub-domains (A and B) [A40060]. … This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101].
Products: UMAN ALBUMIN200G/L, ALBÚMINA HUMANA 200G/L3-amino-5-phenylpentane
go.drugbank.com/drugs/DB02869Experimentaland cathepsin L2. … These are compounds containing a phenylpropylamine moiety, which consists of a phenyl group substituted at the third carbon by a propan-1-amine. 3-amino-5-phenylpentane targets the proteins cathepsin K
Warfarin
go.drugbank.com/drugs/DB00682ApprovedInvestigationalAlthough originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: Nu-warfarinTA-NIC
go.drugbank.com/drugs/DB05445InvestigationalTA-NIC is a novel and proprietary vaccine in development as an aid to quitting smoking in motivated patients.
Synonyms: TA-NICAluminium monostearate
go.drugbank.com/drugs/DB01375ExperimentalAluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2.
Binodenoson
go.drugbank.com/drugs/DB04853InvestigationalBinodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A<sub>2A</sub> receptor. … This specificity allows Binodenoson to deliver - in a single injection - a more effective dose of medication with fewer side effects than current treatments, which typically require a 15-20 minute infusion
L523S
go.drugbank.com/drugs/DB06498Investigational[A175909] It has been investigated as a lung cancer vaccine. … According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S)
Vinorelbine
go.drugbank.com/drugs/DB00361ApprovedInvestigationalIt is a third-generation vinca alkaloid. … A study was done on the clearance rate of vinorelbine on individuals with various single polymorphonuclear mutations.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index