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Midostaurin
go.drugbank.com/drugs/DB06595ApprovedInvestigationalIt was approved on April 28, 2017 and has shown to increase the overall survival rate in patients with AML as an adjunct therapy along with chemotherapeutic agents.
Seletracetam
go.drugbank.com/drugs/DB05885InvestigationalIt binds to the same target as levetiracetam but with higher affinity and has shown potent seizure suppression in models of acquired and genetic epilepsy with high CNS tolerability.
Carboprost tromethamine
go.drugbank.com/drugs/DB00429ApprovedInvestigationalA nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
International brands: Prostin 15MCitraconic acid
go.drugbank.com/drugs/DB04734ExperimentalCitraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Beclamide
go.drugbank.com/drugs/DB09011ExperimentalIt was studied in the 1950s for generalised tonic-clonic seizures but was not effective for absence seizures.
KUR-113
go.drugbank.com/drugs/DB18413InvestigationalKUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone fragment. It is being investigated as a bioactive bone graft substitute.
Altropane
go.drugbank.com/drugs/DB04947InvestigationalBoston Life Sciences (BLS) is developing Altropane as a potential radio-imaging agent to be used with single photon emission tomography (SPECT), for the early diagnosis of Parkinson's disease (PD) and attention deficit hyperactivity diso...
Cadaverine
go.drugbank.com/drugs/DB03854ExperimentalCadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine.
Lortalamine
go.drugbank.com/drugs/DB09187ExperimentalThis drug never made it past clinical trials, likely due to ocular toxicity in animals, but has been used in positron emission tomography studies to label norepinephrine transporters.