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go.drugbank.com/drugs/DB05484InvestigationalIn pre-clinical studies, HuMax-Inflam has been shown to inhibit tumor growth in tumor models using primary human tumors in immunodeficient mice. … MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation.
Synonyms: HuMax IL-8, HuMax-IL-8H3B-8800
go.drugbank.com/drugs/DB14017InvestigationalH3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine [L2551].
Categories: Heterocyclic Compounds, 1-RingSynonyms: (2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(2-pyridinyl)-2,4-heptadien-2-yl]oxacyclododec-4-en-6-yl 4-methyl-1-piperazinecarboxylate, (2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-Dimethyl-12-Oxo-2-[(2E,4E,6R)-6-(Pyridin-2-Yl)Hepta-2,4-Dien-2-Yl]Oxacyclododec-4-En-6-Yl 4-Methylpiperazine-1-CarboxylateMethyl salicylate
go.drugbank.com/drugs/DB09543ApprovedInvestigationalVet approvedIt forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen. … It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments.
Synonyms: 2-Carbomethoxyphenol, 2-(Methoxycarbonyl)phenolMixtures: ValleGel Prep, TOKUSEN MEDICAL PLASTERAllylestrenol
go.drugbank.com/drugs/DB01431InvestigationalA synthetic steroid with progestational activity.
Synonyms: 17α-allylestr-4-en-17β-ol, 3-deketo-17α-allyl-19-nortestosteroneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLasmiditan
go.drugbank.com/drugs/DB11732ApprovedInvestigationalhowever, and their vasoconstrictive activity can lead to blood pressure lability and other cardiovascular side effects - for this reason, these medications are less suitable for use in patients with pre-existing … [A187322,A187319] Selectivity for 5-HT<sub>1F</sub>, a lack of vasoconstrictive activity, and the ability to terminate migraines through neuronal inhibition has resulted in the creation of a new class
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: 1 RayvowHydroxyurea
go.drugbank.com/drugs/DB01005ApprovedInvestigationalHydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: N-Hydroxyurea, N-CarbamoylhydroxylamineTipifarnib
go.drugbank.com/drugs/DB04960InvestigationalTipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. … In June 2005, the FDA issued a Not Approvable Letter for Zarnestra.
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-RingDaclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnDespite being approved for use, Zinbryta (daclizumab)'s complex pre-existing safety profile consisting of its restricted availability through a Risk Evaluation and Mitigation Strategy program [L1738] and … on 2 March 2018 [L1738].
Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyPoliovirus type 2 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10796ApprovedInvestigationalPoliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis … caused by poliovirus Type 2.
Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADETSynonyms: Poliovirus vaccine inactivated, type 2 (MEF-1), Inactivated poliomyelitis vaccine (D.C.O.) type 2 MEF1Tetrahydrocannabivarin
go.drugbank.com/drugs/DB11755InvestigationalTetrahydrocannabivarin (THCV) is a propyl analogue of tetrahydrocannabinol (Δ9-THC), one of the primary pharmacological components of [Medical Cannabis]. … As a major phytocannabinoid, however, THCV is accessible within [Medical Cannabis] along with other identified cannabinoids including [Cannabidiol] (CBD), [cannabinol] (CBN), [cannabigerol] (CBG), [cannabichromene
Categories: Serotonin 5-HT1 Receptor Agonists