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Displaying results 461 - 470 of 1640 in total
  1. Drug

    Capsaicin

    go.drugbank.com/drugs/DB06774
    ApprovedInvestigational

    The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia.

  2. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.

    Categories: Serotonin Receptor Antagonists, Serotonin 3 Receptor Antagonists
  3. Drug

    Abiprubart

    go.drugbank.com/drugs/DB19333
    Investigational

    Abiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395

    Synonyms: Immunoglobulin G4-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], humanized monoclonal antibody
  4. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

  5. Target

    Endothelin receptor type B

    go.drugbank.com/bio_entities/BE0000043
    TargetHumans

    Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

    Polypeptides: Endothelin receptor type BSynonyms: Endothelin receptor non-selective type
  6. Target

    Muscarinic acetylcholine receptor M3

    go.drugbank.com/bio_entities/BE0000045
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M3
  7. Target

    Muscarinic acetylcholine receptor M1

    go.drugbank.com/bio_entities/BE0000092
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M1Function: G protein-coupled acetylcholine receptor activity
  8. Target

    Cysteinyl leukotriene receptor 2

    go.drugbank.com/bio_entities/BE0000099
    TargetHumans

    Receptor for cysteinyl leukotrienes. The response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system.

    Polypeptides: Cysteinyl leukotriene receptor 2Synonyms: G protein-coupled receptor HG57, G protein-coupled receptor GPCR21
  9. Target

    Lutropin-choriogonadotropic hormone receptor

    go.drugbank.com/bio_entities/BE0000134
    TargetHumans

    Receptor for lutropin-choriogonadotropic hormone (PubMed:11847099). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099)

    Polypeptides: Lutropin-choriogonadotropic hormone receptorSynonyms: Luteinizing hormone receptor
  10. Target

    Retinoic acid receptor gamma

    go.drugbank.com/bio_entities/BE0000144
    TargetHumans

    Receptor for retinoic acid.

    Polypeptides: Retinoic acid receptor gammaSynonyms: Nuclear receptor subfamily 1 group B member 3