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Erenumab
go.drugbank.com/drugs/DB14039ApprovedInvestigationalIt is composed of 2 heavy chains, each containing 456 amino acids, and 2 light chains of the lambda subclass, each containing 216 amino acids, with an approximate molecular weight of 150 kDa [FDA Label … Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines
Products: PASURTA® 140 MG /ML, AIMOVIG (140 MG/ML SOLUTION FOR INJECTION)Imipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalImipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. … In depressed individuals, imipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexProducts: IMIPRAMINA 10 MG, IMIPRAMIN-NEURAX 10 MGClonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD. Clonidine was granted FDA approval on 3 September 1974.
Mixtures: Combipres 0.1/15 TabCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexIsoniazid
go.drugbank.com/drugs/DB00951ApprovedInvestigationalAntibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Mixtures: RIFAMPICIN 150 MG/ISONIAZID 150 MG, RIFAMPICIN 150 MG/ISONIAZID 150 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsQuaternium-15
go.drugbank.com/drugs/DB14198ApprovedSensitivity to Quaternium-15 may be identified with a clinical patch test. … Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics.
Synonyms: Quaternium 15Pyridostigmine
go.drugbank.com/drugs/DB00545ApprovedInvestigationalMyasthenia gravis is an autoimmune disease involving dysfunction at the neuromuscular junction, most commonly due to autoantibodies directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, a...
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: MESTINON TABLET 10 mg, MİYASTU 180 MG UZATILMIŞ SALIMLI TABLET, 30 ADETFlutemetamol (18F)
go.drugbank.com/drugs/DB09151ApprovedInvestigationalFlutemetamol (18F), an analogue of [(11)C]PIB,[A18519] is a radioactive diagnostic drug used for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density.
Categories: Compounds used in a research, industrial, or household settingProducts: VİZAMYL 150 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 MLAcemetacin
go.drugbank.com/drugs/DB13783ApprovedInvestigational[A31352] In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.[T50] It was developed by E. … Acemetacin is a carboxymethyl ester of indometacin.
Products: RANTUDİL 90 MG UZATILMIŞ SALIMLI KAPSÜL, 10 ADET, RANTUDIL ® LP 90 MG CAPSULAS DE LIBERACIÓN PROLONGADAMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Mixtures: L-OMBRIX-DUET, L-OMBRIX-DUETProducts: L-OMBRIX, Pantelmin 100 mg - TablettenErgoloid mesylate
go.drugbank.com/drugs/DB01049Approved[T90] The derivatives of this fungus are identified to be about 350 different substances from which the components of the ergoloid mesylate mixture are composed of the dihydrogenated ergot alkaloid derivatives
Mixtures: TOTERJİN DAMLA, 50 CCCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates