Search
Apomorphine
go.drugbank.com/drugs/DB00714ApprovedInvestigational[A203597,A203618] Apomorphine was granted FDA approval on 20 April 2004.[L13919] … It was first synthesized in 1845 and first used in Parkinson's disease in 1884.
Categories: Heterocyclic Compounds, 2-Ring, Drugs Used in Erectile DysfunctionSynonyms: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diolPhenobarbital
go.drugbank.com/drugs/DB01174ApprovedInvestigationalIt promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Mixtures: PIROFEN 200 MG/15 MG SUPPOZITUAR, 50 ADET, PIROFEN 200 MG/15 MG SUPPOZITUAR, 10 ADETCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesBuspirone
go.drugbank.com/drugs/DB00490ApprovedInvestigationalIt has also been used as a second-line therapy for unipolar depression when the use of selective serotonin reuptake inhibitors (SSRIs) is deemed clinically inadequate or inappropriate. … [A180985] First synthesized in 1968 then patented in 1975,[L7375] it is commonly marketed under the brand name Buspar®.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dioneQuinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigational[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [A184844] Quinapril was granted FDA approval on 19 November 1991.[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423]
Mixtures: ACCUZIDE FORT 20 MG/25 MG FILM KAPLI TABLET, 30 ADET, ACCUZIDE 20 MG/12.5 MG FILM TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin SystemAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigationalLong-acting formulations of psychostimulants (such as [DB00422], [DB01576], and [DB01255]) are typically considered the most effective and first-line treatment for ADHD in adults and children as recommended … More recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: FIXATOM 10 MG KAPSÜL, 28 ADET, ATTEX 10 MG KAPSÜL, 28 ADETDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalIt is the active descarboethoxy metabolite of loratidine (a second generation histamine). … Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Mixtures: DELOFED MR 2.5/120 MG KAPSUL, 20 ADET, DELODAY PLUS 120 MG/2,5 MG EFERVESAN TABLET, 20 ADETSynonyms: 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridineTrimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsSynonyms: 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine, 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineMethenamine
go.drugbank.com/drugs/DB06799ApprovedInvestigationalVet approvedIn salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Mixtures: PURINOL 250 mg+615 mg/5 g EFERVESAN 140 GR, PURINOL 250 mg+615 mg/5 g EFERVESAN 140 GRProducts: URON 500 MG TABLET, 21 ADET, URON 500 MG TABLET, 1000 ADETCyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalIt has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. … Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxideUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceuticalFrom its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. … [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation.
Salts: Coenzyme q10, (2z)-Mixtures: Coen.q10w.vit.c and E Beta-car.se Cu Zn Mn, Medi-10