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Displaying results 4711 - 4720 of 10000 in total
  1. Drug

    Octreotide

    go.drugbank.com/drugs/DB00104
    ApprovedInvestigational

    Acromegaly is a life-threatening disease requiring life-long management. … Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: SANDOSTATIN VIALES PARA DOSIS MULTIPLE 1 MG/ 5 ML, SANDOSTATIN® LAR® 30 MG MICROESFERAS PARA INYECCION
  2. Drug

    Oxolamine

    go.drugbank.com/drugs/DB13216
    Approved

    Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant [L5416]. It is listed as a prescription drug in New Zealand legislation [L5419]. … Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflamation [L5422].

    Mixtures: KATARIN FORT 650 MG/200 MG/60 MG/4 MG FİLM KAPLI TABLET, 20 ADET, KATARIN 120 MG+50 MG+1 MG/5 ML PEDIATRIK SURUP 100 MLCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Amphotericin B

    go.drugbank.com/drugs/DB00681
    ApprovedInvestigational

    Amphotericin B shows a high order of in vitro activity against many species of fungi. … ranging from 0.03 to 1.0 mcg/mL in vitro.

    Synonyms: AMPH-b, Amfotericina BSalts: Amphotericin B Cholesteryl Sulfate Complex
  4. Drug

    Rifamycin

    go.drugbank.com/drugs/DB11753
    ApprovedInvestigationalWithdrawn

    The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid. … Product which allowed it to have a status a priority review.

    Mixtures: RIFETEM 250 MG / 3 ML AMPUL, 1 ADET, RİF 250 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (1 AMPUL)Categories: Heterocyclic Compounds with 4 or More Rings, MATE 1 Inhibitors
  5. Drug

    Milrinone

    go.drugbank.com/drugs/DB00235
    ApprovedInvestigational

    Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. … [A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function and peripheral vasodilation in acute decongested heart failure.

    Mixtures: Milrinone Lactate in DextroseCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  6. Drug

    Methadone

    go.drugbank.com/drugs/DB00333
    ApprovedInvestigational

    Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. … (due to a lack of active metabolites), minimal accumulation in renal failure, good bioavailability, low cost, and a long duration of action.

    Synonyms: 6-Dimethylamino-4,4-diphenyl-3-heptanoneCategories: Drugs Used in Opioid Dependence, Drugs Used in Addictive Disorders
  7. Drug

    Menadione

    go.drugbank.com/drugs/DB00170
    ApprovedNutraceutical

    A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

    Mixtures: LIBAVIT-K 20 MG AMPUL, 5 ADETCategories: Vitamin K, Cytochrome P-450 CYP1A2 Inducers
  8. Drug

    Mepolizumab

    go.drugbank.com/drugs/DB06612
    ApprovedInvestigational

    Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm<sup>3</sup> or more) is associated with a spectrum … Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline.

    Categories: Interleukin-5 AntagonistProducts: Nucala 40 mg/0,4 mL S.C. Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (1 adet), Nucala 40 mg/0,4 mL S.C. Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (3 adet)
  9. Drug

    Iron protein succinylate

    go.drugbank.com/drugs/DB11209
    Approved

    Mixtures: FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK.Products: KOMFER 40 MG ORAL ÇÖZELTİ, 15 ML X 10 FLAKON, KOMFER 40 MG ORAL ÇÖZELTİ, 15 ML X 20 FLAKON
  10. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Mixtures: Lasitace 5 mg/40 mg Kapseln, Trinomia 100 mg/40 mg/5 mg HartkapselnCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin System