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Displaying results 4731 - 4740 of 10000 in total
  1. Drug

    BI 2536

    go.drugbank.com/drugs/DB16107
    Investigational

    BI 2536 is under investigation in clinical trial NCT00376623 (Efficacy and Safety of BI 2536 in Advanced or Metastatic Non Small Cell Lung Cancer).

  2. Drug

    Sutetinib

    go.drugbank.com/drugs/DB18841
    Investigational

    Sutetinib is under investigation in clinical trial NCT05168566 (Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer).

    Synonyms: (2e)-n-(3-cyano-7-ethoxy-4-((3-ethynylphenyl)amino)-6-quinolinyl)-4-(dimethylamino)-2-butenamide, 2-butenamide, n-(3-cyano-7-ethoxy-4-((3-ethynylphenyl)amino)-6-quinolinyl)-4-(dimethylamino)-, (2e)-
  3. Drug

    GPI-0100

    go.drugbank.com/drugs/DB05929
    Investigational

    The GPI-0100 adjuvant, which has been shown to significantly enhance the immune response with a variety of vaccines, has been shown to have good overall performance characteristics on safety and efficacy

  4. Drug

    Navitoclax

    go.drugbank.com/drugs/DB12340
    Investigational

    Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, … Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of lymphomas and other types of cancer.

    Synonyms: (R)-4-(3-Morpholin-4-Yl-1-Phenylsulfanylmethyl-Propylamino)-N-(4-{4-[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex-1-Enylmethyl]-Piperazin-1-Yl}-Benzoyl)-3-Trifluoromethanesulfonylbenzenesulfonamide
  5. Drug

    Butorphanol

    go.drugbank.com/drugs/DB00611
    ApprovedIllicitVet approved

    It is used in the management of severe pain.

    Synonyms: (−)-N-cyclobutylmethyl-3,14-dihydroxymorphinan
  6. Drug

    Oglufanide

    go.drugbank.com/drugs/DB05779
    Investigational

    Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before … being acquired by Implicit Bioscience in 2005.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Rabusertib

    go.drugbank.com/drugs/DB11662
    Investigational

    Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer.

  8. Drug

    Carbon black

    go.drugbank.com/drugs/DB11980
    Investigational

    Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment [A263396] with demonstrated adverse effects on pulmonary function. … [A263401] Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and has been linked to carcinogenicity.[A263406, A263411, A263416]

    Synonyms: VEGETABLE CARBON (E 153)
  9. Drug

    Etarfolatide

    go.drugbank.com/drugs/DB11810
    Investigational

    Etarfolatide has been used in trials studying the treatment and diagnostic of Breast Neoplasms, Non Small Cell Lung Cancer, and Adenocarcinoma of the Lung.

  10. Drug

    Tulmimetostat

    go.drugbank.com/drugs/DB19446
    Investigational

    Tulmimetostat is under investigation in clinical trial NCT05467748 (EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer).

    Synonyms: (2R)-7-chloro-2-[trans-4-(3-methoxyazetidin-1-yl)cyclohexyl]-2,4-dimethyl-N-{[6-methyl-4-(methylsulfanyl)-2-oxo-1,2-dihydropyridin-3-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide, 1,3-Benzodioxole-5-carboxamide, 7-chloro-N-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(3-methoxy-1-azetidinyl)cyclohexyl]-2,4-dimethyl-, (2R)-