Search
Etynodiol
go.drugbank.com/drugs/DB13866ExperimentalEtynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDornase alfa
go.drugbank.com/drugs/DB00003ApprovedInvestigationalIn individuals with cystic fibrosis, extracellular DNA, which is an extremely viscous anion, is released by degenerating leukocytes that accumulate during inflammatory responses to infections.
Mephenytoin
go.drugbank.com/drugs/DB00532ApprovedWithdrawnThese are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. Mephenytoin is known to target sodium channel protein type 5 subunit alpha.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesFibrinolysin
go.drugbank.com/drugs/DB05254InvestigationalThe light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da. … The combination is available as ointment containing 1 BU (Biological Unit) Fibrinolysin and 666 BUs desoxyribonuclease per gram.
Otilonium
go.drugbank.com/drugs/DB13500InvestigationalMixtures: BROMURO DE OTILONIO + SIMETICONA 40MG + 200MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDTX-101
go.drugbank.com/drugs/DB17699InvestigationalDTX-101 is an investigational gene therapy consisting of an adeno-associated virus serotype Rh10 vector encoding the human Factor Ix gene.
Anti-SARS-CoV-2 IgY
go.drugbank.com/drugs/DB16356InvestigationalFrom there, the chicken antibodies are harvested from the egg yolks of the eggs laid by these chickens and formulated into the nasal drops that can be administered. … [L27381] To create these antibodies, chickens are injected in the chest with the spike protein, which is the surface protein of SARS-CoV-2; this results in an immune response mounted by the chickens towards
NS-3728
go.drugbank.com/drugs/DB05835ExperimentalNS3728 is an orally active chloride channel blocker for the treatment of cancer.
Sotagliflozin
go.drugbank.com/drugs/DB12713ApprovedInvestigational[L39739] On March 22, 2022, the marketing authorization of sotagliflozin for the treatment of type 1 diabetes mellitus was withdrawn by the EMA due to commercial reasons. … Sotagliflozin is a dual inhibitor of SGLT1 and SGLT2, the first of its kind,[A244499] which is approved for use in the EU, in combination with insulin, to improve glycemic control in patients with type
Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates