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Displaying results 4731 - 4740 of 7058 in total
  1. Drug

    Pemivibart

    go.drugbank.com/drugs/DB18720
    Investigational

    Pemivibart (Pemgarda) is a human IgG1 monoclonal antibody targeting the SARS-CoV-2 spike protein receptor binding domain. … [L50326] It received emergency use authorization (EUA) from the FDA in March 2024 for pre-exposure prophylaxis (PrEP) of COVID-19 in certain high-risk patient populations.

  2. Drug

    Phosphorus P-32

    go.drugbank.com/drugs/DB14551
    Investigational

    Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. … Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular

  3. Drug

    Tipifarnib

    go.drugbank.com/drugs/DB04960
    Investigational

    In June 2005, the FDA issued a Not Approvable Letter for Zarnestra. … Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer.

  4. Drug

    Stepronin

    go.drugbank.com/drugs/DB01423
    Experimental

    Strepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties. … The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA.

  5. Drug

    Alizapride

    go.drugbank.com/drugs/DB01425
    Investigational

    Alizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects.

    Categories: Dopamine D2 Receptor Antagonists
  6. Drug

    SPC2968

    go.drugbank.com/drugs/DB06351
    Investigational

    It was under investigation in clinical trial NCT02564614 (A Study of Hypoxia-inducible Factor 1a (HIF1A) Messenger Ribonucleic Acid (mRNA) Antagonist (RO7070179), to Demonstrate Proof-of-mechanism in Adult … SPC2968 is a synthetic antisense oligodeoxynucleotide targeting hypoxia-inducible factor-1alpha (HIF-1alpha).

  7. Drug

    LY-2584702

    go.drugbank.com/drugs/DB12690
    Investigational

    LY2584702 has been used in trials studying the treatment of Cancer, Advanced Cancer, Renal Cell Carcinoma, Metastases, Neoplasm, and Neuroendocrine Tumors, among others.

    Categories: Ribosomal Protein S6 Kinases, 70-kDa, antagonists & inhibitors
  8. Drug

    Remoxipride

    go.drugbank.com/drugs/DB00409
    ApprovedWithdrawn

    Remoxipride is an atypical antipsychotic agent that is specific for dopamine D<sub>2</sub> receptors.

    Categories: Dopamine D2 Receptor Antagonists
  9. Drug

    JNJ-37822681

    go.drugbank.com/drugs/DB12579
    Investigational

    JNJ-37822681 has been used in trials studying the treatment of Schizophrenia.

    Categories: Dopamine D2 Receptor Antagonists
  10. Drug

    Tioguanine

    go.drugbank.com/drugs/DB00352
    ApprovedInvestigational

    An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.