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Amibegron

Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.

Mebanazine

It was used in the past as an antidepressant in the 1960s, but has since been discontinued because of its hepatotoxic potential.

TRX1

TRX1 is a humanized antibody that binds to the CD4 receptor found on a subset of T cells. … TRX1 is being developed for the potential treatment of autoimmune diseases in collaboration with Genentech, Inc. TolerRx is currently conducting a Phase I clinical study of TRX1 in the United Kingdom.

3-hydroxyanthranilic acid

An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.

Phosphate ion

AstraZeneca COVID-19 Vaccine

[L32649,L32664] In March 2021, several EU member countries halted the administration of AstraZeneca's COVID-19 Vaccine due to signals of an increased risk of blood clots associated with thrombocytopenia … across the globe, including Canada, Mexico, the UK, the EU, and Australia, amongst others.

ANA971

ANA971 resulted in higher levels of isatoribine in the blood than were present after oral administration of isatoribine itself. … ANA971, an orally administered prodrug of isatoribine. Isatoribine is a nucleoside analog in development for the treatment of chronic hepatitis C virus (HCV) infection.

Calcium cation

Ocrylate

Ocrylate is under investigation in clinical trial NCT01918059 (Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive).

Etofamide

Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued [L5617].