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Multipotent adult arogenitor cells
go.drugbank.com/drugs/DB15742InvestigationalThe cells for creation of the product are isolated from a qualified donor and expanded on a large scale and then frozen until use. After administration, the cells are cleared from the body over time. … Like mesenchymal stem cells, MAPCs are derived from bone-marrow stroma and are non-hematopoietically adherent.
Oxiconazole
go.drugbank.com/drugs/DB00239ApprovedIt is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm. … Oxiconazole is an antifungal agent that is commonly found in topical formulations.
Categories: Imidazole and Triazole Derivatives, Genito Urinary System and Sex HormonesLenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigationalHIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens … [L42995] On December 22, 2022, it was also approved by the FDA.[L44473]
Sodium sulfide
go.drugbank.com/drugs/DB11159ApprovedAlong with its hydrate form, sodium sulfide releases hydrogen sulfide (H2S) when in contact with moist air. … H2S is an endogenous gaseous transmitter that exhibits anti-inflammatory and antiapoptotic properties.
Spirapril
go.drugbank.com/drugs/DB01348ApprovedInvestigationalACE inhibitors are used primarily in treatment of hypertension and congestive heart failure. … Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.
Categories: Amino Acids, Peptides, and ProteinsAlunacedase alfa
go.drugbank.com/drugs/DB15736InvestigationalAlunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsBavituximab
go.drugbank.com/drugs/DB05136InvestigationalIt binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4. … Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections.
Categories: Amino Acids, Peptides, and ProteinsBetrixaban
go.drugbank.com/drugs/DB12364ApprovedBetrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [A7708]. … VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [A27287].
Categories: Blood and Blood Forming OrgansIMC-1C11
go.drugbank.com/drugs/DB06101ExperimentalIMC-1C11 is used for treatment of patients with liver metastases from colorectal carcinoma. … IMC-1C11 is an anti-angiogenesis agent.
Categories: Amino Acids, Peptides, and ProteinsPreviously treated with an HCV regimen containing sofosbuvir without an NS5A inhibitor Chronic hepatitis C genotype 3
go.drugbank.com/conditions/DBCOND0093782Drugs: VoxilaprevirSynonyms: Previously treated with an HCV regimen containing sofosbuvir without an NS5A inhibitor Chronic hepatitis C genotype 3