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rdESAT-6
go.drugbank.com/drugs/DB21906ApprovedrdESAT-6 is a recombinant dimer of _Mycobacterium tuberculosis_ early secretory antigenic target used as an ingredient in the diagnostic agent SIILTIBCY along with [rCFP-10].[L53638]
Synonyms: rdESAT-6Elamipretide
go.drugbank.com/drugs/DB11981ApprovedInvestigational[A274436] Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane. … [L54036] In September 2025, the U.S.
Categories: MATE 1 InhibitorsAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigationalAnifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus. … , which may alter patient responses in the experimental and placebo groups; and patient populations were largely homogenous, which may have increased the odds of success of the trial.
Categories: Type I Interferon Receptor AntagonistProducts: Saphnelo 300 mg/2 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADETVilanterol
go.drugbank.com/drugs/DB09082ApprovedInvestigationalIncreases in cyclic AMP are associated with the relaxation of bronchial smooth muscle and inhibition of the release of hypersensitivity mediators from mast cells in the lungs. … [L46481,L44461,L44456] BREO ELLIPTA is the first vilanterol-containing product to be approved by the FDA in May 2013, followed by ANORO ELLIPTA in December 2013 and TRELEGY ELLIPTA in September 2020.
Mixtures: RELVAR® ELLIPTA® 100MCG/25MCG, RELVAR® ELLIPTA ® 200MCG/25MCG POLVO PARA INHALACIÓNCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesFlurpiridaz F-18
go.drugbank.com/drugs/DB18773ApprovedFlurpiridaz F-18 is a radioactive diagnostic drug indicated for positron emission tomography (PET) myocardial perfusion imaging (MPI), which is an imaging process used in patients with known or suspected … [A264519] Flurpiridaz F-18 is an analog of pyridaben, a mitochondrial complex 1 (MC-1) inhibitor.[L51659]
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-tert-butyl-4-chloro-5-((4-((2-(18f)fluoroethoxy)methyl)phenyl)methoxy)pyridazin-3(2h)-one, 2-tert-butyl-4-chloro-5-[[4-(2-(18F)fluoranylethoxymethyl)phenyl]methoxy]pyridazin-3-oneBazedoxifene
go.drugbank.com/drugs/DB06401ApprovedInvestigationalthe prevention of postmenopausal osteoporosis in women. … In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis.
Categories: Sex Hormones and Modulators of the Genital System, Heterocyclic Compounds, 2-RingGadoquatrane
go.drugbank.com/drugs/DB33282Approvedin the central nervous system and in the body. … [L63814] Like other gadolinium agents it is paramagnetic, developing a magnetic moment in the scanner's field that alters the relaxation of nearby water protons and brightens tissues with abnormal vascularity
Categories: Diagnostic Uses of ChemicalsCarisoprodol
go.drugbank.com/drugs/DB00395Approvedfor abuse in addition to a low risk of dependence [L5074]. … This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and codeine [FDA label, F4060, F4069].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSynonyms: N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate, (1-methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl esterSipuleucel-T
go.drugbank.com/drugs/DB06688ApprovedInvestigationalThe treatment initially cost $93,000 at the time of FDA approval, but rose to over $100,000 in 2014. … Sipuleucel-T selectively targets the prostate-specific antigen (PSA) known as prostatic acid phosphatase (PAP) that is expressed in around 95% of prostate cancers.
Synonyms: Sipuleucel-TCategories: sipuleucel-T, Intercellular Adhesion Molecule-1Brilliant green cation
go.drugbank.com/drugs/DB11279ApprovedVet approvedDue to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection. … Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool.
Mixtures: Kerr 100 Triple Dye Dispos-ACategories: Compounds used in a research, industrial, or household setting