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VIR201
go.drugbank.com/drugs/DB05110ExperimentalThe aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.
Benazeprilat
go.drugbank.com/drugs/DB14125ExperimentalCategories: Agents Acting on the Renin-Angiotensin SystemTengonermin
go.drugbank.com/drugs/DB16689Investigational[A233270] A study also demonstrated that binding of the NGR-motif to CD13 determined both the homing of NGR-hTNF to tumor vessels and the increase in its antiangiogenic activity.[A233270] … [A233270] Literature demonstrates that NGR-peptides bind to a CD13 isoform, of which expression is restricted to tumor vasculature cells.
Brentuximab
go.drugbank.com/drugs/DB05471Investigationalto on normal cells. … It is available commercially as the monoclonal antibody portion of the antibody-drug conjugate [brentuximab vedotin].
Tigapotide
go.drugbank.com/drugs/DB04985InvestigationalTigapotide is a synthetic 15-mer peptide that is derived from the natural sequence of amino acids of the prostate secretory protein (PSP94), one of three predominant proteins found in human seminal fluid
Etelcalcetide
go.drugbank.com/drugs/DB12865ApprovedInvestigationalEtelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. … Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Categories: Calcium-sensing Receptor Agonist, Increased Calcium-sensing Receptor SensitivityGinsenoside Rg1
go.drugbank.com/drugs/DB06750ExperimentalNutraceuticalGinsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. … Because ginsenosides appear to affect multiple pathways, their effects are complex and difficult to isolate. Rg1 Appears to be most abundant in Panax ginseng (Chinese/Korean Ginseng).
Retinoic acid-induced protein 3
go.drugbank.com/bio_entities/BE0000697TargetHumansOrphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells.
Synonyms: G protein-coupled receptor family C group 5 member AVLA-4 (very late antigen-4)
go.drugbank.com/bio_entities/BE0010014TargetHumansIntegrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. … Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1.
Synonyms: Fibronectin receptor subunit betaNACHT, LRR and PYD domains-containing protein 3
go.drugbank.com/bio_entities/BE0010347TargetHumansSensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis (PubMed:16407889, PubMed:1840367...
Synonyms: Angiotensin/vasopressin receptor AII/AVP-like