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Displaying results 471 - 480 of 8415 in total
  1. Drug

    Ciprofloxacin

    go.drugbank.com/drugs/DB00537
    ApprovedInvestigational

    Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. … [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.[L6463]

    Products: PMS-ciprofloxacin, PMS-ciprofloxacin XL
  2. Drug

    Cimetidine

    go.drugbank.com/drugs/DB00501
    ApprovedInvestigational

    Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output.

    Products: PMS-cimetidine
  3. Drug

    Valsartan

    go.drugbank.com/drugs/DB00177
    ApprovedInvestigational

    [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension in adults. Shortly after, in 1997, this drug was approved in the United States. … The angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized.

    Mixtures: PMS-valsartan-hctz, PMS-valsartan-hctzProducts: PMS-valsartan
  4. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval in the US in 1995.[L12207] … It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels.

    Mixtures: PMS-sitagliptin-metformin, PMS-sitagliptin-metforminProducts: PMS-metformin, PMS-metformin - Tab 500mg
  5. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.

    Products: PMS-theophylline Elixir
  6. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    [A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults. … [A175249] Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel antidiabetic drug.[A188330]

    Products: PMS-topiramate, AS-TOPIRAM 200 MG FILM TABLET
  7. Drug

    Mefenamic acid

    go.drugbank.com/drugs/DB00784
    Approved

    A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.

    Products: PMS-mefenamic Acid
  8. Drug

    Ritonavir

    go.drugbank.com/drugs/DB00503
    ApprovedInvestigational

    Ritonavir is found in a fixed-dose combination product with [DB09296], [DB09183], and [DB09297] as the FDA-approved product Viekira Pak. … In Canada, ritonavir is also available as a fixed-dose combination product with [DB09296], [DB09183], and [DB09297] as the Health Canada-approved, commercially available product Holkira Pak.

    Mixtures: Viekira Pak, Holkira Pak
  9. Drug

    Etoperidone

    go.drugbank.com/drugs/DB09194
    ApprovedWithdrawn

    Etoperidone is an atypical antidepressant introduced in Europe in 1977. … [T45] Etoperidone was developed by Angelini Francesco ACRAF.[A4909]

  10. Drug

    Grape seed oil

    go.drugbank.com/drugs/DB14323
    Investigational

    Grape seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: European Grape Seed Oil