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Cyproheptadine
go.drugbank.com/drugs/DB00434ApprovedInvestigational[L32474] It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation[L32519] and its off-label use in the treatment of serotonin syndrome.
Synonyms: 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidineProducts: PMS-cyproheptadine HCl Tab 4mg, Periactin Tab 4mgMitoxantrone
go.drugbank.com/drugs/DB01204ApprovedInvestigationalAn anthracenedione-derived antineoplastic agent.
Products: MITOXANTRONE BAXTER SOLUTION FOR INJECTION 20MG/10ML (2MG/ML), Novantrone Inj 2mg/mlSiltuximab
go.drugbank.com/drugs/DB09036ApprovedInvestigationalIt is administered as a 1 hour intravenous infusion every 3 weeks.
Products: Sylvant 400mg Powder for Concentrate for Solution for Infusion, Sylvant 100mg Powder for Concentrate for Solution for InfusionDapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalIt is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
Products: Dapsone 25mg, Dapsone 100mgMoclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalDue to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A31901]. … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (
Products: PMS-moclobemide, Manerix Tab 100mgChlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnChlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy (UKPDS-33). … It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin.
Products: Diabinese Tab 100mg, Apo Chlorpropamide Tab 100mgFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalIt is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Synonyms: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazineProducts: NATIL N 10MG, FLUNAVERT 10MGMethylnaltrexone
go.drugbank.com/drugs/DB06800ApprovedInvestigationalIt is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Products: Relistor Solution For Injection 12mg/0.6mL, RELISTOR (TM) (SUBCUTANEOUS INJECTION,12MG/0.6ML PER VIAL)Ketorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigational[L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511] … Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.
Mixtures: ONEMER DTProducts: KINE 10MG, Toradol Tab 10mgPropofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedPropofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medic...
Products: PROPOFOL 10MG / ML, CRIXOFOL 10MG/1MLAMPOLLA POR 20 ML