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Diphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalAs histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the … However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352].
Mixtures: NOIMSON D TABLETAS 500 MG, Acetaminophen / Diphenhydramine 500/25 mgCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSafinamide
go.drugbank.com/drugs/DB06654ApprovedInvestigationalIt was approved in Europe in February 2015, and in the United States on March 21, 2017.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: XADAGO 100 MG TABLETASRECUBIERTAS CON PELÍCULA, Equfina Film coated Tablets 50 mgBilastine
go.drugbank.com/drugs/DB11591ApprovedBilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Products: Nasitop 10 mg Schmelztabletten, BILAXTEN 20 MG TABLET ,10 TABLETDexibuprofen
go.drugbank.com/drugs/DB09213ApprovedWithdrawnDexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability [A19259].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: TRADIL 200 MG FILM TABLET, 50 ADET, TRADIL 300 MG FILM TABLET, 50 ADETFluphenazine
go.drugbank.com/drugs/DB00623ApprovedA phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol, 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanolPropylthiouracil
go.drugbank.com/drugs/DB00550ApprovedA thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharma...
Products: TIROSTAT 100, PROPYL TABLET 50 mgNaltrexone
go.drugbank.com/drugs/DB00704ApprovedInvestigationalVet approvedThe FDA has approved naltrexone for the treatment of alcohol dependence. … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction.
Products: Addex-1000, NARPAN TABLET 50 mgValganciclovir
go.drugbank.com/drugs/DB01610ApprovedInvestigationalAs the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Products: AVALCEPT 50 MG / ML ORAL ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 100 ML, Valcyte 50 mg/ml - Pulver zur Herstellung einer Lösung zum EinnehmenAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approvedA benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: 5-(propylthio)-2-carbomethoxyaminobenzimidazole, O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamatePiroxicam
go.drugbank.com/drugs/DB00554ApprovedInvestigationalA cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its lon...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: ROXIFEN GEL 500 mg/100 g, Felden 10 mg - Kapseln