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Displaying results 471 - 480 of 10000 in total
  1. Drug

    Amsacrine

    go.drugbank.com/drugs/DB00276
    ApprovedInvestigationalWithdrawn

    Aminoacridine derivative that is a potent intercalating antineoplastic agent. … It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors.

    Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsSynonyms: 4'-(9-Acridinylamino)methanesulfon-m-anisidide, 4'-(9-Acridinylamino)methanesulphon-m-anisidide
  2. Drug

    Flavone

    go.drugbank.com/drugs/DB07776
    ApprovedInvestigational

    Synonyms: 2-phenyl-4H-1-benzopyran-4-one, 2-Phenyl-4-chromoneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  3. Drug

    4-Sulfonamide-[4-(Thiomethylaminobutane)]Benzamide

    go.drugbank.com/drugs/DB04002
    Experimental

    Synonyms: 4-Sulfonamide-[4-(Thiomethylaminobutane)]Benzamide
  4. Drug

    Iptacopan

    go.drugbank.com/drugs/DB16200
    ApprovedInvestigational

    B. … Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor

    Categories: Compounds used in a research, industrial, or household setting, Complement Factor B InhibitorSynonyms: 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid, BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)-
  5. Drug

    Bumetanide

    go.drugbank.com/drugs/DB00887
    ApprovedInvestigational

    Bumetanide is a sulfamyl diuretic.

    Mixtures: BURINEX TABLET 1 mg, BURINEX TABLET 1 mgSynonyms: 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid, 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid
  6. Drug

    Thiabendazole

    go.drugbank.com/drugs/DB00730
    ApprovedVet approvedWithdrawn

    2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 2-(thiazol-4-yl)benzimidazole, 4-(2-benzimidazolyl)thiazole
  7. Drug

    N-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide

    go.drugbank.com/drugs/DB07152
    Experimental

    Synonyms: N-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide
  8. Drug

    Naloxone

    go.drugbank.com/drugs/DB01183
    ApprovedInvestigationalVet approved

    [L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.

    Mixtures: Bupensan Duo 4 mg/1 mg-Sublingualtabletten, TILIDIN 50/4 RETARD 1A PHACategories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein substrates
  9. Drug

    Lisuride

    go.drugbank.com/drugs/DB00589
    Approved

    An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).

    Synonyms: N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylureaCategories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 Substrates
  10. Drug

    CH-1504 L-isomer

    go.drugbank.com/drugs/DB19052
    Investigational

    CH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).

    Synonyms: L-m-trex, 4-methylene-n-(4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)-l-glutamic acid