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Displaying results 471 - 480 of 10000 in total
  1. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    [L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. … [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.

    Synonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamineProducts: RIZATRIPTAN EG
  2. Drug

    Buflomedil

    go.drugbank.com/drugs/DB13510
    Investigational

    Products: BUFLOMEDIL EG
  3. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine. … Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight.

    Categories: Drugs Used in DiabetesProducts: REPAGLINIDE EG
  4. Drug

    Indobufen

    go.drugbank.com/drugs/DB12545
    Investigational

    Indobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.

    Products: INDOBUFENE EG
  5. Drug

    Sultopride

    go.drugbank.com/drugs/DB13273
    Approved

    Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics [L5626].

  6. Drug

    Azacitidine

    go.drugbank.com/drugs/DB00928
    ApprovedInvestigational

    [A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved by the FDA in September 2020.[L35335] … It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine.

    Products: AZACITIDINA EG
  7. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Categories: Arteriolar Smooth Muscle, Agents Acting OnProducts: TRIATOP®ESPUMA TÓPICA EN AEROSOL, TYLCORE® ESPUMA TÓPICA EN AEROSOL
  8. Drug

    Carbidopa

    go.drugbank.com/drugs/DB00190
    ApprovedInvestigational

    therapy developed by Mayne Pharma in 1992. … An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea.

    Mixtures: LEV/CAR/EN AL100/25/200, LEV/CAR/EN AL200/50/200
  9. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423] … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.

    Synonyms: 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazoleMixtures: LOSARTAN E IDROCLOROTIAZIDE EG, LOSARTAN E IDROCLOROTIAZIDE EG
  10. Drug

    Perindopril

    go.drugbank.com/drugs/DB00790
    ApprovedInvestigational

    It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration.

    Mixtures: PERINDOPRIL E AMLODIPINA EG, PERINDOPRIL E AMLODIPINA EGCategories: Agents Acting on the Renin-Angiotensin System