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Displaying results 471 - 480 of 10000 in total
  1. Drug

    (1Z)-2-HYDROXY-3-OXOHEX-1-EN-1-YL DIHYDROGEN PHOSPHATE

    go.drugbank.com/drugs/DB06881
    Experimental

    Synonyms: (1Z)-2-HYDROXY-3-OXOHEX-1-EN-1-YL DIHYDROGEN PHOSPHATE
  2. Drug

    Vandetanib

    go.drugbank.com/drugs/DB05294
    ApprovedInvestigational

    Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types. … On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine, N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  3. Drug

    Ammonio methacrylate copolymer type A

    go.drugbank.com/drugs/DB12031
    Investigational

    Ammonio methacrylate copolymer type a has been used in trials studying the treatment of GERD.

    Synonyms: Ammonio methacrylate copolymer type AInternational brands: Eudragit RL 30 D
  4. Drug

    Oxybutynin

    go.drugbank.com/drugs/DB01062
    ApprovedInvestigational

    It is often used as first-line therapy for OAB.[A185990] … Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat, 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
  5. Drug

    Influenza a virus, inactivated hemagglutinin

    go.drugbank.com/drugs/DB33834
    Experimental

    Synonyms: Influenza a virus, inactivated hemagglutinin
  6. Drug

    Benzoylpas

    go.drugbank.com/drugs/DB19382
    ApprovedWithdrawn

    Synonyms: Benzoic acid, 4-(benzoylamino)-2-hydroxy-, 4-benzamidosalicylate
  7. Drug

    Rotavirus vaccine

    go.drugbank.com/drugs/DB10276
    ApprovedInvestigational

    Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains.[L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain. … [Label] Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection.[L1117]

    Salts: Human Rotavirus A type G1P(8) strain RIX4414 live antigen, Human Rotavirus A type G1P7(5) strain WI79 live antigenMixtures: ROTATEQ® VACUNA ORAL PENTAVALENTE CONTRAROTAVIRUS, ROTATEQ® VACUNA ORAL PENTAVALENTE CONTRAROTAVIRUS
  8. Drug

    Cannabidivarin

    go.drugbank.com/drugs/DB14050
    Investigational

    , which is a member of a large family of ion channels that are involved in the onset and progression of several types of epilepsy. … CBDV has also been shown to inhibit the activity of diacylglycerol (DAG) lipase-α, the primary enzyme responsible for the synthesis of the endocannabinoid, 2-arachidonoylglycerol (2-AG) [A33296, A33347

    Synonyms: 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol, CBD-V
  9. Drug

    Diosmetin

    go.drugbank.com/drugs/DB11259
    Approved

    It also acts as a weak TrkB receptor agonist [A27230]. … Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits [A27231].

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone, 3',5,7-trihydroxy-4'-methoxyflavone
  10. Drug

    Acetyldigitoxin

    go.drugbank.com/drugs/DB00511
    Approved

    Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Desglucolanatoside A, Digitoxin 3'''-acetate