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Displaying results 471 - 480 of 5498 in total
  1. Drug

    Fenfluramine

    go.drugbank.com/drugs/DB00574
    ApprovedIllicitInvestigationalWithdrawn

    It is currently sold under the name FINTEPLA® by Zogenix INC.[L14522] … It is characterized by recurrent pharmacoresistant seizures, which increase in frequency and severity with disease progression.

    Products: Pondimin Tab 20mg
  2. Drug

    Orphenadrine

    go.drugbank.com/drugs/DB01173
    ApprovedInvestigational

    A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

    Products: Disipal Tab 50mg, Norflex tablet 100mg
  3. Drug

    Dimethicone

    go.drugbank.com/drugs/DB11074
    ApprovedInvestigational

    On skin, it is also observed to have moisturizing actions [L1771, L1773]. … It is used in a number of health and beauty products including hair care products such as shampoo, conditioner, leave-in conditioner, and de-tangling products.

    Mixtures: Antacid and Anti-Gas Chew, E-Z-gas IIProducts: Siero Chee Cheek Coral, Siero Chee Cheek Classy Pink
  4. Drug

    Afoxolaner

    go.drugbank.com/drugs/DB11369
    ExperimentalVet approved

    Mixtures: Nexgard Spectra 150mg/30mg Chewable Tablets for Dogs >30-60kg, Nexgard Spectra 9mg/2mg Chewable Tablets for Dogs 2-3.5kgProducts: NexGard 28mg chewable tablets for dog > 4-10kg, NexGard 11mg chewable tablets for dogs 2-4kg
  5. Drug

    Nefopam

    go.drugbank.com/drugs/DB12293
    ApprovedInvestigationalWithdrawn

    Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.

    Products: ACUPAN SOLUTION FOR INJECTION 20MG/2ML
  6. Drug

    Pergolide

    go.drugbank.com/drugs/DB01186
    ApprovedVet approvedWithdrawn

    It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. … It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome. It was later found that pergolide increased the risk of cardiac valvulopathy.

    Products: PERGOLIDE EG, Permax Tab 1mg
  7. Drug

    Testosterone

    go.drugbank.com/drugs/DB00624
    ApprovedInvestigational

    Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine...

    International brands: Bio-T-GelProducts: Malogen Aqueous 100 Sus 100mg/ml, Androgel 50mg
  8. Drug

    Darifenacin

    go.drugbank.com/drugs/DB00496
    ApprovedInvestigational

    This block reduces the urgency to urinate and so it should not be used in people with urinary retention. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.

    Products: EMSELEX 15MG RET, DARUCIL® ER 15 MG
  9. Drug

    Cilostazol

    go.drugbank.com/drugs/DB01166
    ApprovedInvestigational

    It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing calcium-induced contractions.

    Products: CILOSTAZOLO EG, CILOSTAZOL AL 50MG TAB
  10. Drug

    Varenicline

    go.drugbank.com/drugs/DB01273
    ApprovedInvestigational

    The FDA said it is keeping the black box in place at least until the results of the trial are announced. … In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S.

    Products: Champix Tablet 1mg, CHAMPIX 1.0MG FILM-COATED TABLETS