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Glial cell line-derived neurotrophic factor
go.drugbank.com/bio_entities/BE0002486TargetHumansNeurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake (PubMed:8493557). Acts by binding to its coreceptor, GFRA1, leading to autophosphoryla...
Polypeptides: Glial cell line-derived neurotrophic factorHuman allogeneic bone marrow derived osteoblastic cells
go.drugbank.com/drugs/DB17890InvestigationalSynonyms: Human allogeneic bone marrow derived osteoblastic cells, Human allogeneic bone-marrow-derived osteoblastic cellsItraconazole
go.drugbank.com/drugs/DB01167ApprovedInvestigational[L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. … While the intravenous formulation of the drug was formerly available, it was discontinued in the US in 2007.[A263232]
Products: ITRACONAZOLO EGRepaglinide
go.drugbank.com/drugs/DB00912ApprovedInvestigationalRepaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). … Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight.
Categories: Drugs Used in DiabetesProducts: REPAGLINIDE EGAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalIn March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. … 9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl group at the 9a position on
Products: AZITROMICINA EG, AZITROMICINA EG STADAMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigationalMorphine was granted FDA approval in 1941.[L12114] … Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Synonyms: (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol, (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diolProducts: Kadian ER, Arymo ERFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigationalThe manufacturer and the FDA advise health professionals to limit the use of febuxostat to second-line therapy in patients who have inadequate response or intolerance to allopurinol, and to avoid the use … [A230548] In February 2019, a black box warning for febuxostat was added, based on the findings of a post-market clinical study (the CARES trial) where there was an increased risk of cardiovascular
Products: FEBUXOSTAT EGHuman autologous bone marrow derived osteoblastic cells
go.drugbank.com/drugs/DB18259InvestigationalSynonyms: Human autologous bone marrow derived osteoblastic cellsBOC-GAMMA-D-GLU-L-LYS(CBZ)-D-BOROALA
go.drugbank.com/drugs/DB04647ExperimentalSynonyms: BOC-GAMMA-D-GLU-L-LYS(CBZ)-D-BOROALAVildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigational[L32803] Vildagliptin is also available as Eucreas, a fixed-dose formulation with metformin for adults in who do not adequately glycemic control from monotherapy. … [A232488] Oral vildagliptin was approved by the European Medicines Agency in 2008 for the treatment of type II diabetes mellitus in adults as monotherapy or in combination with [metformin], a sulfonylurea
Mixtures: GALVUS® MET 50/500 COMPRIMIDOS RECUBIERTOS CON PELICULA, GALVUS® MET COMPRIMIDO RECUBIERTO CON PELICULA 50 MG/850 MGCategories: Drugs Used in Diabetes