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Chlorambucil
go.drugbank.com/drugs/DB00291ApprovedInvestigationalAlthough it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed) … A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases.
Synonyms: N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid, N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acidProducts: LEUKERAN 2 MG TABLET, 25 ADET, Leukeran 2 mg - FilmtablettenAmorolfine
go.drugbank.com/drugs/DB09056ApprovedWithdrawnIt is available in the form of a 5% amorolfine nail lacquer used to treat onychomycosis (fungal infection of the toe- and fingernails). … Amorolfine 5% nail lacquer in once or twice weekly applications is 60-71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment (after six months of treatment
Categories: Heterocyclic Compounds, 1-RingProducts: RAZOLE %5 TIRNAK CILASI, 5 ML, RAZOLE %5 TIRNAK CILASI, 2.5 MLOxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalefficacy since initial FDA approval in 1975. … Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat, 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolateFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalFluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. … HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2B6 InducersProducts: Fluvastatin Sandoz 20 mg - Hartkapseln, LESCOL XL 80 MG TABLET, 28 ADETSpesolimab
go.drugbank.com/drugs/DB15626ApprovedInvestigationalIt is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. … in December 2022 for the treatment of flares in adult patients with generalized pustular psoriasis.
Products: Spevigo 450 mg/7,5 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 2 ADETDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigationalDorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and … [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.
Mixtures: DORZOLOL® UD, Cosopt 20 mg/ml + 5 mg/ml AugentropfenCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingRanolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigational[L3580] With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.[L5440] … Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities.
Categories: MATE 2 Inhibitors, MATE 1 InhibitorsProducts: RANEXICOR ® 500, RANEXICOR ® 1000Duloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more.
Synonyms: (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine, (S)-duloxetineCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesBenzylpenicillin
go.drugbank.com/drugs/DB01053ApprovedInvestigationalVet approvedPenicillin G may also be used in some cases as prophylaxis against susceptible organisms. … Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria.
Synonyms: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, Penicillin GMixtures: Bicillin C-R 900/300, Bicillin A-P Injection PwsPeramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalfor no more than two days. … The injectable intravenous formulation of peramivir was approved by the FDA in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and older who have been symptomatic
Products: Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (5 Adet), Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (3 Adet)