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Displaying results 4791 - 4800 of 10000 in total
  1. Drug

    Tisagenlecleucel

    go.drugbank.com/drugs/DB13881
    ApprovedInvestigational

    Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy, or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. … Tisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual patient and genetically engineered to express a specific protein called a chimeric

    Synonyms: Tisagenlecleucel-T, CAR.CD19-Redirected T cellsCategories: Genetically-modified Autologous T Cells
  2. Drug

    Human cytomegalovirus immune globulin

    go.drugbank.com/drugs/DB13886
    ApprovedInvestigational

    Cytomegalovirus (CMV) may lead to a wide spectrum of infection in immunocompetent hosts. … It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label].

    Categories: Immunoglobulin G, Human Immunoglobulin GProducts: MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML
  3. Drug

    Meningococcal polysaccharide vaccine group Y

    go.drugbank.com/drugs/DB13888
    ApprovedInvestigational

    *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. … Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified from *Neisseria meningitidis* serogroup Y.

    Synonyms: Neisseria meningitidis group Y polysaccharide antigen, A, Meningococcal polysaccharide antigen group YMixtures: Menomune - A/c/y/w-135 Combined, Menomune-A/c/y/w-135
  4. Drug

    Crotalus adamanteus antivenin

    go.drugbank.com/drugs/DB13893
    Approved

    Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age...

  5. Drug

    Talimogene laherparepvec

    go.drugbank.com/drugs/DB13896
    ApprovedInvestigational

    It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities.

    Synonyms: T Vec, T-VecCategories: Complex Mixtures
  6. Drug

    Equine Botulinum Neurotoxin E Immune FAB2

    go.drugbank.com/drugs/DB13897
    Approved

    Equine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype E. … It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes E in adults and pediatric patients.

    Synonyms: Botulinum Neurotoxin E immune FAB2 (equine), BOTULINUM NEUROTOXIN E IMMUNE FAB2, EQUINE
  7. Drug

    Equine Botulinum Neurotoxin C Immune FAB2

    go.drugbank.com/drugs/DB13898
    Approved

    Equine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype C. … It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes C in adults and pediatric patients.

    Synonyms: Botulinum Neurotoxin C immune FAB2 (equine), BOTULINUM NEUROTOXIN C IMMUNE FAB2, EQUINE
  8. Drug

    Equine Botulinum Neurotoxin B Immune FAB2

    go.drugbank.com/drugs/DB13903
    Approved

    Equine Botulinum Neurotoxin B Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype B. … It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes B in adults and pediatric patients.

    Synonyms: Botulinum Neurotoxin B immune FAB2 (equine), BOTULINUM NEUROTOXIN B IMMUNE FAB2, EQUINE
  9. Drug

    Cat dander extract

    go.drugbank.com/drugs/DB13904
    Approved

    It is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats.

  10. Drug

    2'-C-methylcytidine

    go.drugbank.com/drugs/DB13921
    Experimental

    A nucleoside analog with anti-hepatitis C virus (HCV) activity. … Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity.

    Synonyms: 2'C-Me-C, 2'-C-MecytosinCategories: Heterocyclic Compounds, 1-Ring