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Methscopolamine
go.drugbank.com/drugs/DB11315ApprovedThe oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications. … Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products.
Agomelatine
go.drugbank.com/drugs/DB06594ApprovedInvestigationalThe Committee for Medical Products for Human Use (CHMP) recommended refusal of marketing authorization on 27 July 2006. The major concern was that efficacy had not been sufficiently shown. … Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
Products: VALDOXAN 25 MG, VALDOXAN® 25 MGMK-8777
go.drugbank.com/drugs/DB18904InvestigationalMK-8777 is under investigation in clinical trial NCT00610649 (Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder
NRP409
go.drugbank.com/drugs/DB05235ExperimentalNRP409 is a triiodothyronine (T3) hormone, being investigated by New River Pharmaceuticals as a treatment for patients with primary hypothyroidism.
SO-101
go.drugbank.com/drugs/DB05345ExperimentalDoxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day. … SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia.
Bacillus calmette-guerin substrain tice live antigen
go.drugbank.com/drugs/DB10343ApprovedInvestigationalBacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of *Mycobacterium bovis* for percutaneous … It is administered to prevent the development of tuberculosis.
Succinobucol
go.drugbank.com/drugs/DB05399InvestigationalAGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary
Gastric inhibitory polypeptide
go.drugbank.com/drugs/DB15217InvestigationalGastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without
CRx-401
go.drugbank.com/drugs/DB05775ExperimentalIt consists of a low dose of the analgesic diflunisal in conjunction with a modified-release therapeutic dose of bezafibrate, an anti-cholesterol agent. … of bezafibrate through novel disease-targeted mechanisms.
Davalintide
go.drugbank.com/drugs/DB14956InvestigationalDavalintide is under investigation in clinical trial NCT00785408 (Study to Examine Safety, Tolerability and Effect on Body Weight of Subcutaneous AC2307 in Obese or Overweight Subjects).