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AMB-301
go.drugbank.com/drugs/DB18094Experimental[L48101] It is under investigation for the treatment of Buerger disease.
GX-G8
go.drugbank.com/drugs/DB18196ExperimentalGX-G8 is a long-acting glucagon-like peptide 2 (GLP-2) being investigated for the treatment of short bowel syndrome.
Col-Treg
go.drugbank.com/drugs/DB18451ExperimentalCol-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.[A261635]
Synonyms: Purified autologous type 1 regulatory T lymphocytes specific for human type II collagenAllisartan isoproxil
go.drugbank.com/drugs/DB18880InvestigationalAllisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).
Yeast beta-D-glucan
go.drugbank.com/drugs/DB19271InvestigationalYeast beta-D-glucan is under investigation in clinical trial NCT00632008 (Soluble Beta-glucan (SBG) as Treatment for Diabetic Foot Ulcers).
Desoxyribonuclease
go.drugbank.com/drugs/DB09551ApprovedInvestigationalDesoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. … The enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration of the ion is independent of the enzyme concentration [A31251].
Mixtures: FIBRASE SASynonyms: Deoxyribonuclease AMuvalaplin
go.drugbank.com/drugs/DB21568InvestigationalMuvalaplin is under investigation in clinical trial NCT05563246 (A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events). … Muvalaplin has a monoisotopic molecular weight of 710.4 Da.
IR501
go.drugbank.com/drugs/DB06464ExperimentalIR501 (Ravax) is a potential first-in-class vaccine for the treatment of Rheumatoid Arthritis. It specifically targets autoreactive T-cells, reducing their activity.
VTP-201227
go.drugbank.com/drugs/DB05652ExperimentalVTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment of psoriasis with potential extensions into other dermatological indications.
Tigapotide
go.drugbank.com/drugs/DB04985InvestigationalTigapotide is a synthetic 15-mer peptide that is derived from the natural sequence of amino acids of the prostate secretory protein (PSP94), one of three predominant proteins found in human seminal fluid