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Smilagenin
go.drugbank.com/drugs/DB05450InvestigationalPre-clinical work with smilagenin showed it to be neuroprotective against betya-amyloid and glutamate damage which contributes to Alzheimer's disease and reverses the changes in the area of the brain involved
COVID19 s-vax loaded autologous dendritic cell vaccine
go.drugbank.com/drugs/DB15814ExperimentalThe rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can induce a more prolific immune response.
Catridecacog
go.drugbank.com/drugs/DB09310ApprovedIt is subsequently isolated by homogenization of cells and purification by several chromatography steps, including hydrophobic interaction and ion exchange chromatography [FDA Label].
Fezolinetant
go.drugbank.com/drugs/DB15669ApprovedInvestigational[L46422] It was subsequently approved by the EMA in December 2023 for the same indication.[L50086]
AGRO100
go.drugbank.com/drugs/DB04998InvestigationalAGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. Such binding leads to internalization of the complex, and...
Multipotent adult arogenitor cells
go.drugbank.com/drugs/DB15742InvestigationalMultiStem is an intravenously-administered, off-the-shelf proprietary product developed which comprises Multipotent Adult Progenitor Cells (MAPCs). Like mesenchymal stem cells, MAPCs are derived from bone-marrow stroma and are non-hemato...
Grazoprevir
go.drugbank.com/drugs/DB11575ApprovedIt can be used in patients with compensated cirrhosis, human immunodeficiency virus co-infection, or severe kidney disease.
Rauwolfia serpentina root
go.drugbank.com/drugs/DB09363InvestigationalIt is a compound commonly used in Asian medicine, which includes traditional Ayurvedic medicine native to India.
Maxy-G34
go.drugbank.com/drugs/DB05718InvestigationalIt is being developed by Maxygen, Inc. for the treatment of chemotherapy-induced neutropenia.