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Displaying results 4861 - 4870 of 10000 in total
  1. Drug

    Matuzumab

    go.drugbank.com/drugs/DB05101
    Investigational

    Matuzumab (formerly known as the experimental drug, EMD 72000) is a humanized monoclonal antibody used in cancer treatment. … It has a high affinity for EGFR (epithelial growth factor receptor), frequently associated with the growth of blood vessels in malignancy, facilitating tumor growth and survival.

  2. Drug

    Cariporide

    go.drugbank.com/drugs/DB06468
    Experimental

  3. Drug

    Carmustine

    go.drugbank.com/drugs/DB00262
    ApprovedInvestigational

    A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: N,N'-Bis(2-chloroethyl)-N-nitrosourea
  4. Drug

    Nefazodone

    go.drugbank.com/drugs/DB01149
    ApprovedWithdrawn

    Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with the incidence of severe liver damage was shown to be approximately 1 in 250,000 to … Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury.

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsSynonyms: 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one
  5. Drug

    Plumbagin

    go.drugbank.com/drugs/DB17048
    Investigational

    Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 5-hydroxy-2-methyl-1,4-naphthalenedione
  6. Drug

    Refametinib

    go.drugbank.com/drugs/DB06309
    Investigational

  7. Drug

    Acetylcysteine zinc

    go.drugbank.com/drugs/DB14479
    Investigational

    Synonyms: N-acetyl-L-cysteine zinc saltCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Calmangafodipir

    go.drugbank.com/drugs/DB18398
    Investigational

    Synonyms: Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine) manganese complexes trisodium trihydrogen manganate, Calmangafodipir (ca4mn(dpdp)5)Categories: Compounds used in a research, industrial, or household setting, Vitamin B Complex
  9. Drug

    Colforsin

    go.drugbank.com/drugs/DB02587
    Investigational

    Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also...

    Synonyms: 7β-acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-oneCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors
  10. Drug

    Quinacrine mustard

    go.drugbank.com/drugs/DB02240
    Experimental

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 3-Ring