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Trioxsalen
go.drugbank.com/drugs/DB04571ApprovedWithdrawnTrioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative obtained from several plants, mainly Psoralea corylifolia. … cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 6-hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid, δ-lactone, 2',4,8-TrimethylpsoralenFleroxacin
go.drugbank.com/drugs/DB04576ExperimentalFleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Fleroxacin is not an inhibitor of CYP1A2.[A39048]
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingAldosterone
go.drugbank.com/drugs/DB04630InvestigationalA hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
Categories: P-glycoprotein inducers, P-glycoprotein substratesSynonyms: (11β)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al, 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-alCarboxin
go.drugbank.com/drugs/DB04657ApprovedWithdrawnA systemic agricultural fungicide and seed treatment agent.
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingSynonyms: 5,6-Dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide, 2,3-Dihydro-5-carboxanilido-6-methyl-1,4-oxathiinCoumarin
go.drugbank.com/drugs/DB04665InvestigationalSynonyms: 2H-1-benzopyran-2-one, 2H-benzo(b)pyran-2-oneCategories: Vitamin K Antagonists, Cytochrome P-450 Substrates2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one
go.drugbank.com/drugs/DB04716ExperimentalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one, CMP 6Gentamicin C1a
go.drugbank.com/drugs/DB04729ExperimentalCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexSulfatide
go.drugbank.com/drugs/DB04780ExperimentalAny of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.
Synonyms: 2-hydroxytetracosanoyl sulfatide, 2-hydroxytetracosanoylgalactosylceramide sulfateZomepirac
go.drugbank.com/drugs/DB04828ApprovedWithdrawnThe manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983. … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acidAmineptine
go.drugbank.com/drugs/DB04836ApprovedIllicitWithdrawnThe Food and Drug Administration suspended the marketing authorisation for Survector in 1999 and France withdrew it from the market, however several developing countries continued to produce it up until 2005.