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Displaying results 4871 - 4880 of 10000 in total
  1. Drug

    ACA 125

    go.drugbank.com/drugs/DB05489
    Investigational

    To create ACA-125, a hybridoma cell was adapted to serum-free medium and antibody was produced in a hollow fiber cell culture system. Positive clinical results are now being reported. … ACA-125 mimics the tumor-associated antigen CA-125, which can be detected in about 80% of ovarian carcinomas.

  2. Target

    Signal recognition particle protein

    go.drugbank.com/bio_entities/BE0001792
    TargetThermus aquaticus

    Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.

    Synonyms: Fifty-four homolog
  3. Drug

    Emricasan

    go.drugbank.com/drugs/DB05408
    Investigational

    It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis. … Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA.

  4. Drug

    TL-895

    go.drugbank.com/drugs/DB16471
    Investigational

    TL-895 is under investigation in several clinical trials for its safety and efficacy in various conditions: NCT04419623 (completed, COVID-19 in cancer patients), NCT02825836 (active, not recruiting, B … TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC50 and a Ki of 1.5 nM and 11.9 nM, respectively.

    Categories: Experimental Unapproved Treatments for COVID-19
  5. Drug

    Iofetamine I-123

    go.drugbank.com/drugs/DB09480
    Approved

    Salts: Iofetamine hydrochloride I-123Categories: Compounds used in a research, industrial, or household setting, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  6. Drug

    Enpatoran

    go.drugbank.com/drugs/DB16501
    Investigational

    Enpatoran (M5049) was under investigation in clinical trials for various conditions. … It was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327).

    Categories: Experimental Unapproved Treatments for COVID-19
  7. Drug

    Atrazine

    go.drugbank.com/drugs/DB07392
    Experimental

    Atrazine is a selective triazine herbicide. Inhalation hazard is low and there are no apparent skin manifestations or other toxicity in humans.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Cythioate

    go.drugbank.com/drugs/DB11392
    ExperimentalVet approved

    Cythioate is a member of the organothiophosphate compounds that is used as an insecticide and anthelmintic. It is mainly used in veterinary as a treatment for fleas.

    Categories: Compounds used in a research, industrial, or household setting
  9. Target

    Sulfotransferase 2A1

    go.drugbank.com/bio_entities/BE0000886
    TargetEnzymeHumans

    Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. … In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols (By similarity)

    Synonyms: Bile salt sulfotransferase
  10. Drug

    Veltuzumab

    go.drugbank.com/drugs/DB05656
    Investigational

    Veltuzumab is a monoclonal antibody which, as of October 2009, is undergoing Phase I/II clinical trials for the treatment of non-Hodgkin's lymphoma.