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Veligrotug
go.drugbank.com/drugs/DB18976Approved[L63798] Thyroid eye disease has historically been managed differently depending on whether it is caught in the active inflammatory phase or has become chronic - Viridian describes veligrotug-vvze as the … Veligrotug is a humanized IgG1 monoclonal antibody that binds the insulin-like growth factor-1 receptor and blocks ligand-induced receptor autophosphorylation, interrupting IGF-1R signaling.
Synonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human-Mus musculus monoclonal VRDN-001 γ1-chain), disulfide with human-Mus musculus monoclonal VRDN-001 κ-chain, dimerGarenoxacin
go.drugbank.com/drugs/DB06160ExperimentalGarenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Categories: Topoisomerase II InhibitorsRusalatide
go.drugbank.com/drugs/DB05309InvestigationalTP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified as the fibroblast high-affinity receptor binding domain.
Human interferon omega-1
go.drugbank.com/drugs/DB05472InvestigationalHuman interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally related to IFN-alpha and -beta. … It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering.
Synonyms: IFN-ωPI-166
go.drugbank.com/drugs/DB05859ExperimentalPI-166 is a small organic compound with specific avidity to liver cancer cells. … It has demonstrated the ability to reduce the growth of rat hepatomas, which is like human hepatomas, are resistant to established anti-cancer agents.
Epinastine
go.drugbank.com/drugs/DB00751ApprovedIt has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding … Epinastine is used for the prevention of itching associated with allergic conjunctivitis.
Synonyms: 3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepineInternational brands: Kai lai ZhiTamibarotene
go.drugbank.com/drugs/DB04942InvestigationalTamibarotene is a novel synthetic retinoid for acute promyelocytic leukaemia (APL). … Tamibarotene is currently approved in Japan for treatment of recurrent APL, and is undergoing clinical trials in the United States.
Madecassoside
go.drugbank.com/drugs/DB15532InvestigationalSynonyms: Asiaticoside AMixtures: Karatica Im Cica Essence PackPatupilone
go.drugbank.com/drugs/DB03010InvestigationalEpothilone B is a 16-membered macrolide that mimics the biological effects of taxol.