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ATP-dependent 6-phosphofructokinase, muscle type
go.drugbank.com/bio_entities/BE0012586TargetHumansCatalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
Synonyms: PFK-A, 6-phosphofructokinase type AZopiclone
go.drugbank.com/drugs/DB01198ApprovedInvestigationalZopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.
Synonyms: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylateCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingFe(3+) ABC transporter substrate-binding protein
go.drugbank.com/bio_entities/BE0002664TargetPasteurella haemolyticaPolypeptides: Fe(3+) ABC transporter substrate-binding proteinSynonyms: Periplasmic iron binding protein A FbpAPhospholipase A1
go.drugbank.com/bio_entities/BE0002041TargetEscherichia coli (strain K12)Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant ...
Synonyms: DR-phospholipase A, Outer membrane phospholipase ATeriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalTeriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. … The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide.
Synonyms: (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidideCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersSultamicillin
go.drugbank.com/drugs/DB12127ApprovedWithdrawnSultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: TYCLAR® 250MG/5ML POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL., BACTESUL 1 G/ 5 MLInterferon alpha-2
go.drugbank.com/bio_entities/BE0003450TargetHumansProduced by macrophages, IFN-alpha have antiviral activities
Synonyms: LeIF A, Interferon alpha-AEnuresis
go.drugbank.com/conditions/DBCOND0018540Drugs: ImipramineSynonyms: Enuresis not due to a substance or known physiological conditionDe Novo Triacylglycerol Biosynthesis TG(10:0/a-13:0/a-13:0)
smpdb.ca/view/SMP0031934MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.
De Novo Triacylglycerol Biosynthesis TG(10:0/a-13:0/a-25:0)
smpdb.ca/view/SMP0031938MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.