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STI-1499
go.drugbank.com/drugs/DB16487InvestigationalSTI-1499 (COVI-GUARD was under investigation in clinical trial NCT04454398 to evaluate its safety and efficacy in patients with moderate COVID-19.
Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15740InvestigationalCurrently, OM-MSCs does not have wide application as there is not yet a standard and unambiguous protocol for OM-MSC collection, isolation, and therapeutic application.
SVV-001
go.drugbank.com/drugs/DB06129InvestigationalSVV-001 has also demonstrated cancer-killing specificity 10,000 times higher than that of traditional chemotherapeutics with no overt toxicity at doses one million times higher than effective doses in … SVV-001 (Seneca Valley Virus) is a novel native picornavirus being developed as a systemically deliverable oncolytic virus for treatment of human cancers with neuroendocrine features.
Danoprevir
go.drugbank.com/drugs/DB11779InvestigationalDanoprevir has been used in trials studying the treatment of Hepatitis C, Chronic.
Vitex agnus-castus fruit extract
go.drugbank.com/drugs/DB13193InvestigationalThe main mechanism of action of vitex agnus-castus fruit extract has not been fully elucidated, however it is suggested to modulate the stress-induced prolactin secretion via dopaminergic actions, and … Clinical studies demonstrates effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and cyclical breast pain (mastalgia).
Epicept NP-1
go.drugbank.com/drugs/DB05492InvestigationalEpiCept NP-1 Cream is a patented formulation containing two FDA-approved drugs, amitriptyline (a widely-used antidepressant) and ketamine (an NMDA antagonist that is used as an anesthetic).
Methylprednisone
go.drugbank.com/drugs/DB12952ApprovedInvestigationalWithdrawnMethylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Diaminopropanol tetraacetic acid
go.drugbank.com/drugs/DB12362ApprovedWithdrawnDiaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others.
mRNA-3351
go.drugbank.com/drugs/DB17718ExperimentalDeveloped by Moderna, it is currently being investigated as the treatment for Crigler-Najjar syndrome
Strontium malonate
go.drugbank.com/drugs/DB05732InvestigationalStrontium malonate is being developed as a novel orally available pharmaceutical for the treatment and prevention of osteoporosis. It is being developed by Osteologix Inc.