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Displaying results 481 - 490 of 7901 in total
  1. Drug

    Methotrexate

    go.drugbank.com/drugs/DB00563
    ApprovedInvestigational

    [A180322] This inhibition leads to suppression of inflammation as well as prevention of cell division. … Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis.

    Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: AC-VONDA, METHOTREXAT AC 50MG/2ML
  2. Drug

    Budesonide

    go.drugbank.com/drugs/DB01222
    ApprovedInvestigational

    Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. … [L10598] It is also available in a combination product with [formoterol].[L10619]

    Mixtures: Combiwave FB 200 (Formoterol Fumarate 6mcg/actuation and Budesonide 200mcg/actuation Pressurised Inhalation)Products: Mylan-budesonide AQ, Budenase AQ Nasal Spray 64 mcg /dose
  3. Drug

    Clobetasol propionate

    go.drugbank.com/drugs/DB01013
    ApprovedInvestigational

    Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.

    Mixtures: SISTEMA GBProducts: CLOBETASOL PROPIONATO CREMA AL 0.05%.
  4. Drug

    Carbocisteine

    go.drugbank.com/drugs/DB04339
    ApprovedInvestigational

    Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. … Carbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the viscosity of mucus, allowing it to be expelled.

    Products: CARBOCISTEINA ABC
  5. Drug

    Carboxymethylcellulose

    go.drugbank.com/drugs/DB11059
    ApprovedInvestigational

    It is added in food products as a viscosity modifier or thickener and emulsifier. … The viscous and mucoadhesive properties as well as its anionic charge allow prolonged retention time in the ocular surface [A33029]. Sodium carboxymethylcellulose is the most commonly used salt.

    Categories: Compounds used in a research, industrial, or household settingProducts: Cho-A Derm, Cho-A Derm-R
  6. Drug

    Calcium carbonate

    go.drugbank.com/drugs/DB06724
    ApprovedInvestigational

    Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. … An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also be used as a nutritional supplement or to treat hypocalcemia.

    Mixtures: Vinate AZ, Prenate AMProducts: L B T A, AI kungang
  7. Drug

    Niraparib

    go.drugbank.com/drugs/DB11793
    ApprovedInvestigational

    Niraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells.

    Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic Index
  8. Drug

    Meloxicam

    go.drugbank.com/drugs/DB00814
    ApprovedInvestigationalVet approved

    It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201] … [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations.

    Mixtures: NURO-B, NURO-BProducts: MELOXICAM AL 15MG TABL, MELOXICAM AL 7.5MG TABL
  9. Drug

    Apixaban

    go.drugbank.com/drugs/DB06605
    ApprovedInvestigational

    Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic

    Products: Ag-apixaban, Nb-apixaban
  10. Drug

    Ephedrine

    go.drugbank.com/drugs/DB01364
    ApprovedInvestigational

    [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. … Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].

    Mixtures: WICK MediNait Erkältungssirup für die Nacht, ColdaeWon Cold AProducts: Sinuplex - Tab, Ephedrine Tab 30mg