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Displaying results 481 - 490 of 10000 in total
  1. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis. … [A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood.

    Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: DIMETILFUMARATO EG
  2. Drug

    Nicotinamide

    go.drugbank.com/drugs/DB02701
    ApprovedInvestigational

    An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. … Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

    Mixtures: Cellmov Cell Line Mask, COMPLEJO B EN KOLA GRANULADAProducts: Snail Essential EX Wrinkle Essence, Costem cell 5 N
  3. Drug

    Fluticasone propionate

    go.drugbank.com/drugs/DB00588
    ApprovedInvestigational

    Fluticasone propionate was first approved in 1990[L5962].

    Mixtures: SALFLUTIN 50/100UG 60 ED, SALFLUTIN 50/250UG 60 EDProducts: FLUTIDE FORTE 500 DISKU ED, FLUTIDE MITE 100 DISKUS ED
  4. Drug

    Lamotrigine

    go.drugbank.com/drugs/DB00555
    ApprovedInvestigational

    Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. … It is approved for use in more than 30 countries.[A191350] Lamotrigine has relatively few side-effects and does not require laboratory monitoring.

    Products: LAMOTRIGINA EG, Lamotrigine ER
  5. Drug

    Clopidogrel

    go.drugbank.com/drugs/DB00758
    ApprovedInvestigational

    [A180547] Clopidogrel was granted FDA approval on 17 November 1997.[L7213] … recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and provides

    Mixtures: CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRIS, CLOPIDOGREL E ACIDO ACETILSALICILICO VIATRISProducts: CLOPIDOGREL EG, CLOPIDOGREL EG STADA
  6. Target

    Protein S100-A12

    go.drugbank.com/bio_entities/BE0001206
    TargetHumans

    S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its pro-inflammatory activity involves recruitment of leukocytes, promotion of cytokine...

    Synonyms: EN-RAGE
  7. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [L56091, L56092] Historically developed in 1945, leucovorin has long been a staple on the World Health Organization’s List of Essential Medicines. … [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic

    Synonyms: N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acidMixtures: Enl
  8. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. … [A179761] Sumatriptan was granted FDA approval on 28 December 1992.[L6805]

    Synonyms: (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamideProducts: SUMATRIPTAN EG, SUMATRIPTAN-HEXAL N 50MG
  9. Drug

    Clarithromycin

    go.drugbank.com/drugs/DB01211
    ApprovedInvestigational

    Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.

    Products: CLARITROMICINA EG, Clarithromycin-hameln 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  10. Drug

    Everolimus

    go.drugbank.com/drugs/DB01590
    ApprovedInvestigational

    In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein. … It is currently used as an immunosuppressant to prevent rejection of organ transplants.

    Products: EVEROLIMUS EG