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Displaying results 481 - 490 of 10000 in total
  1. Drug

    Ertugliflozin

    go.drugbank.com/drugs/DB11827
    ApprovedInvestigational

    [A261951, L1132] It was also approved by the European Commission in March 2018.[L48621] … It works to block glucose reabsorption from the glomerulus.[A31581] Ertugliflozin was first approved by the FDA in December 2017.

    Mixtures: Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated Tablets, Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated TabletsCategories: Drugs Used in Diabetes
  2. Drug

    Somatostatin

    go.drugbank.com/drugs/DB09099
    ApprovedInvestigationalWithdrawn

    It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating … Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 (SST-28), an extended SST-14 sequence to the N-terminus [A20384].

    Products: Stilamin - Pws IV 3mg/amp, STILAMIN 3000 FOR INJECTION 3 mg/ampoule
  3. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. … Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States.

    Mixtures: Darvocet-N 50, Darvocet-N 100Products: Novo-propoxyn Cap 65mg, Darvon-N
  4. Drug

    Ferrous gluconate

    go.drugbank.com/drugs/DB14488
    ApprovedInvestigational

    Mixtures: Multivit Et Fer Ampoules Et Comprimes, Dynam Ampoule Et TabletProducts: Fertinic Syr 35mg/5ml, Timed Release Iron 35mg
  5. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.

    Synonyms: N-(3-methylaminopropyl)iminobibenzylProducts: DESIPRAM 25 MG TABLET, 100 ADET, Norpramin 10mg Tab
  6. Drug

    Carbinoxamine

    go.drugbank.com/drugs/DB00748
    Approved

    Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many

    Mixtures: TEMPRA XT NOCHEProducts: Karbinal ER, CARBIMIN TABLETS 4MG
  7. Drug

    Melatonin

    go.drugbank.com/drugs/DB01065
    ApprovedInvestigationalNutraceuticalVet approved

    In mammals, melatonin is produced by the pineal gland. … Reduced melatonin production has also been proposed as a likely factor in the significantly higher cancer rates in night workers.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 5-methoxy-N-acetyl tryptamine, 5-methoxy-N-acetyltryptamine
  8. Drug

    Polatuzumab vedotin

    go.drugbank.com/drugs/DB12240
    ApprovedInvestigational

    Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. … [L6658] Polatuzumab vedotin was granted accelerated FDA approval on June 10, 2019 [A254936] and was approved by Health Canada on July 9, 2020.[L44141]

    Products: POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 30MG, POLIVY 30mg Powder For Concentrate For Solution For Infusion
  9. Drug

    Cefaclor

    go.drugbank.com/drugs/DB00833
    ApprovedInvestigational

    Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.

    Mixtures: SEFKLAV 250/62.5 MG EFERVESAN TABLET, 20 ADET, SEFKLAV 500/125 MG EFERVESAN TABLET, 20 ADETProducts: CEFACLOR EG, CEFACLOR BASICS 125MG TS
  10. Drug

    Magnesium chloride

    go.drugbank.com/drugs/DB09407
    ApprovedInvestigational

    Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

    Mixtures: SOLUCION DP PISA 2.5%(MODIFICADA EN MAGNESIO Y LACTATO), Gelofusin Iso 40 mg/ml InfusionslösungProducts: Naturogene Tab 36mg