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Displaying results 4911 - 4920 of 10000 in total
  1. Drug

    Deramciclane

    go.drugbank.com/drugs/DB06512
    Investigational

    Deramciclane differs from other anti anxiety medications in that it is not a benzodiazepine and so has a different structure and target. … It antagonizes 5-HT2A receptors, agonizes 5-HT2C receptors, and functions as a GABA reuptake inhibitor.

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  2. Drug

    IL15-NK Cell

    go.drugbank.com/drugs/DB15725
    Investigational

    In particular, incubation with IL-15 allows NK cells to lyse a broad range of fresh and cultured tumor targets that the cell is not normally sensitive to. … Natural killer (NK) cells can be incubated with ‘feeder cells’ expressing certain cytokines prior to maturation to enhance their activity.

  3. Drug

    ALKS 27

    go.drugbank.com/drugs/DB05752
    Experimental

    ALKS 27 is an inhaled formulation of trospium chloride for the treatment of chronic obstructive pulmonary disease (COPD). … Study showed that ALKS 27 was well-tolerated over a wide dose range, with no dose-limited effects observed.

  4. Drug

    Romlusevimab

    go.drugbank.com/drugs/DB16494
    Investigational

    Romlusevimab (BRII-198) was under investigation in clinical trials (NCT04479644 and NCT04691180) to treat COVID-19, focusing on its safety, tolerability, and pharmacokinetics.

    Synonyms: IMMUNOGLOBULIN G1-LAMBDA2, ANTI-(SEVERE ACUTE RESPIRATORYSYNDROME CORONAVIRUS 2 (SARS-COV-2) SPIKE (S) GLYCOPROTEIN,RECEPTOR BINDING DOMAIN (RBD)), HOMO SAPIENS MONOCLONALANTIBODY
  5. Drug

    Butabarbital

    go.drugbank.com/drugs/DB00237
    ApprovedIllicitWithdrawn

    [A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. … Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-ethyl-5-(1-methylpropyl)barbituric acid, 5-ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
  6. Drug

    Tesmilifene

    go.drugbank.com/drugs/DB04905
    Investigational

    Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsSynonyms: N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine
  7. Drug

    Carotuximab

    go.drugbank.com/drugs/DB06322
    Investigational

    Synonyms: ) (1-118) -HOMO SAPIENS IGHG1*01 (119-448)) (221-2, GAMMA1 HEAVY CHAIN (1-448) (MUS MUSCULUS VH (IGHV6-6*01-(IGHD) -IGHJ2*01) (8.10.9) (1-118) -HOMO SAPIENSIGHG1*01, GM17,1 (CH1 (119-216), HINGE (217-231), CH2(232-341), CH3 (342-446), CHS (447-448)) (119
  8. Drug

    SGX-523

    go.drugbank.com/drugs/DB06314
    Investigational

    A MET receptor tyrosine kinase inhibitor.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline
  9. Drug

    Iobenzamic acid

    go.drugbank.com/drugs/DB13428
    Experimental

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, Iodinated
  10. Drug

    Ioglycamic acid

    go.drugbank.com/drugs/DB13741
    Experimental

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, Iodinated